Summary
It was found that ‘in vitro’ lymphocyte cultures from normal individuals transformed non-specifically in response to certain bacterial filtrates. Filtrate treated lymphocytes stimulated autologous lymphocytes in a mixed leucocyte test and treated leukaemic blasts produced higher stimulation of remission lymphocytes than untreated blasts. The relevance of these observations is discussed.
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de Azavedo, J., Greally, J.F. Some ‘in vitro’ effects of bacterial filtrates on normal lymphocytes and leukaemic cells. IJMS 144, 266–273 (1975). https://doi.org/10.1007/BF02939025
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DOI: https://doi.org/10.1007/BF02939025