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Superantigen types inStaphylococcus aureus isolated from patients with cystic fibrosis

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Abstract

The screening of 17 SAg genes ofS. aureus isolated from the sputum of cystic fibrosis (CF) patients revealed that among 47 genetically different strains, 39 (83 %) carried SAg genes. Superantigens forming enterotoxin gene cluster were detected in 20 strains. The 2nd most common superantigen type wasselk detected in 13 strains. In 9 strains,selk occurred together with thesea gene. Out of 74 strains recovered from nasal carriers, 56 (75 %) were found to carry SAg genes, 38 carriedegc genes, whileselk was detected in 5 strains. The predominant SAg types in both investigatedS. aureus populations wereegc andselk/sea, butselk gene frequency was significantly higher in the CF-derived strains.

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Abbreviations

CF:

cystic fibrosis

CFTR:

cystic fibrosis transmembrane conductance regulator

ITPD:

Institute of Tuberculosis and Pulmonary Diseases, Rabka

KPC:

Korozak Pediatric Center of Lower Silesia, Wrocław

MCI:

Mother and Child Institute, Warsaw

PFGE:

pulsed field gel electrophoresis

SAg:

staphylococcal superantigen(s)

SE:

staphylococcal enterotoxin(s)

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Authors and Affiliations

  1. Department of Food Hygiene and Consumer Protection. Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, 50-375, Wrocław, Poland

    J. Bania, J. Bystroń & J. Molenda

  2. Department of Animal Products Technology, Faculty of Food Science, Wrocław University of Environmental and Life Sciences, 50-375, Wrocław, Poland

    A. Dąbrowska, A. Žarczyńska & J. Chrzanowska

  3. Department of Infectious Biology. Institute of Microbiology, University of Łódź, 90-237, Łódź, Poland

    B. Różalska, B. Sadowska & M. Więckowska-Szakiel

  4. Laboratory of Bacteriology and Immunology, Korczak Pediatric Center of Lower Silesia, 51-137, Wrocław, Poland

    K. Korzekwa

Authors
  1. J. Bania
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  2. A. Dąbrowska
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  3. B. Różalska
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  4. B. Sadowska
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  5. M. Więckowska-Szakiel
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  6. K. Korzekwa
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  7. A. Žarczyńska
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  8. J. Bystroń
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  9. J. Chrzanowska
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  10. J. Molenda
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Correspondence to J. Bania.

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Bania, J., Dąbrowska, A., Różalska, B. et al. Superantigen types inStaphylococcus aureus isolated from patients with cystic fibrosis. Folia Microbiol 51, 614–618 (2006). https://doi.org/10.1007/BF02931628

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  • DOI: https://doi.org/10.1007/BF02931628

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