Skip to main content
SpringerLink
Log in

Gas holdup in a three-phase fluidized-bed bioreactor

  • Published:
Applied Biochemistry and Biotechnology Aims and scope Submit manuscript

Abstract

The effects of system parameters on the gas holdup in a three-phase fluidized-bed bioreactor were examined. A valve technique was used to measure the average gas holdup in the reactor. Gas holdup was found to be strongly affected by fluid superficial velocities, bead size and density, electrolyte concentration, type of gas sparger, and temperature. Quantitative and qualitative observations were made regarding the differences between conventional glass-particle systems and low-density gel-particle systems. Most notably, the degree of bubble coalescence and mode of fluidization were highly dependent on each system.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Reference

  1. Andrews, G. (1988),Biotechnol. Genet. Eng. Rev. 6, 151.

    CAS  Google Scholar 

  2. Haas, P. (1975),AIChE J. 21, 383.

    Article  CAS  Google Scholar 

  3. van’t Riet, K. (1983),Trends Biotechnol. 1, 113.

    Article  Google Scholar 

  4. Lessard, R. and Zieminski, S. (1971),Ind. Eng. Chem. Fund. 10, 260.

    Article  CAS  Google Scholar 

  5. Michelsen, M. L. and Ostergaard, K. (1970),Chem. Eng. J. 1, 37.

    Article  CAS  Google Scholar 

  6. Dhanuka, V. R. and Stepanek, J. B. (1978),Proc. Second Eng. Foundation Conf., Davidson, J. F., and Keairns, D. L., eds., Cambridge University Press, Cambridge, UK, 190.

    Google Scholar 

  7. Rice, R., Tupperainen, J., and Hedge, R. (1981),Can. J. of Chem. Eng. 59, 677.

    CAS  Google Scholar 

  8. Graver, G., Rode, C., and Chaudhari, R. (1986),Can. J. of Chem. Eng. 64, 501.

    Article  Google Scholar 

  9. Smith, E. L., Jamialahmadi, M., Olajuyigbe, J. T., and Shayegan Salek, J. (1986),Proc. of BHRA Int. Conf. on Bioreactor Fluid Dynamics, Cambridge, England, p. 677.

  10. Verlaan, P., Tramper, J., van’t Riet, K., and Luyben, K. (1986),Proc. of BHRA Int. Conf. on Bioreactor Fluid Dynamics, Cambridge, England, p. 93.

  11. Verlaan, P., and Tramper, J. (1987),Int. Conf. on Bioreactors and Biotransformations, Gleneagles, Scotland, p. 363.

Download references

Author information

Authors and Affiliations

  1. Department of Chemical Engineering, Michigan State University, 48824, East Lansing, MI

    M. J. Bly & R. M. Worden

Authors
  1. M. J. Bly
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. M. Worden
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bly, M.J., Worden, R.M. Gas holdup in a three-phase fluidized-bed bioreactor. Appl Biochem Biotechnol 24, 553–564 (1990). https://doi.org/10.1007/BF02920278

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02920278

Index Entries

Search

Navigation