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Enzymatic synthesis of neopentylpolyol esters in organic media

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Abstract

Utilization of lipases for synthesis of esters of hydrophilic polyols has been investigated. The choice of a suitable solvent is crucial in this type of reaction. An interesting case is fatty acid esters from neopentylpolyols, such as trimethylolpropane, which are of great interest as high temperature lubricants. Enzymatic synthesis of trimethylolpropane tricaprylate was studied as an alternative to chemical manufacturing. Triester production occurred only if the water produced by esterification was continuously removed from the medium. In these condition, kinetics of appearance and transformation of mono-, di- and triesters were determined in order to define optimal conditions.

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References

  1. Klibanov, A. M. (1986),Chemtech 16, 354.

    CAS  Google Scholar 

  2. Brockman, H. L. (1984),Lipases, Borgström, B., and Brockman, H. L., eds., Elsevier, Amsterdam, The Netherlands, pp. 3–46.

    Google Scholar 

  3. Laane, C., Boeren, S., Hilhorst, R., and Veeger, C. (1987),Biocatalysis in organic media, Laane, C., Tramper, J., and Lilly, M. D., eds., Elsevier, Amsterdam, The Netherlands, pp. 65–84.

    Google Scholar 

  4. Cesti, P., Zaks, A., and Klibanov, A. M. (1985),Appl. Biochem. Biotechnol. 11, 401.

    Article  CAS  Google Scholar 

  5. Therisod, M. and Klibanov, A. M. (1986),J. Am. Chem. Soc. 108, 5638.

    Article  CAS  Google Scholar 

  6. Therisod, M. and Klibanov, A. M. (1987),J. Am. Chem. Soc. 109, 3877.

    Article  Google Scholar 

  7. Bell, G., Blain, J. A., Patterson, J. D. E., Shaw, C. E. L., and Todd, R. (1978),FEMS Microbiol. Lett. 3, 223.

    Article  CAS  Google Scholar 

  8. Meffert, A. (1984),J. Am. Oil Chem. Soc. 61, 255.

    CAS  Google Scholar 

  9. Osada, F., Kobayashi, M., Sachio, A., and Kitazako, H. (1986), Jap. Pat62,296,884.

    Google Scholar 

  10. Novo Industries A/S, Bagsvaerd, Denmark (1983), Analytical method information AF 95/5 GB.

  11. Zaks, A. and Klibanov, A. M. (1985),Proc. Natl. Acad. Sci. USA 82, 3192.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Institut Francais du Pétrole, 1, 4 avenue de Bois Préau, BP 311, 92506, Rueil Malmaison Cedex, France

    Frédéric Monot, Yves Benoit, Daniel Ballerini & Jean-Paul Vandecasteele

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  1. Frédéric Monot
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  2. Yves Benoit
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  3. Daniel Ballerini
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  4. Jean-Paul Vandecasteele
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Monot, F., Benoit, Y., Ballerini, D. et al. Enzymatic synthesis of neopentylpolyol esters in organic media. Appl Biochem Biotechnol 24, 375–386 (1990). https://doi.org/10.1007/BF02920261

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  • DOI: https://doi.org/10.1007/BF02920261

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