Abstract
An immature ovarian teratoma containing adenohypophyseal tissue with a central arteriole and interpositioned in mature neural tissue is reported in an asymptomatic 31 -year-old woman. The tumor was a grade 2 immature teratoma according to the modified ThurlbeckScully histological grading system. Immunocytochemistry showed positive staining for growth hormone, prolactin, adrenocorticotropin, and alpha-subunit human chorionic gonodotropin and negative staining for thyroid-stimulating, follicle-stimulating, and luteinizing hormones in the adenohypophysis. The absence of staining for growth-hormonereleasing and corticotropin-releasing hormones, somatostatin, vasopressin, and neurophysin in adjacent tissue is consistent with the view that adenohypophyseal development is independent of the influence of these peptides.
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Pilavdzic, D., Chiu, B., Kovacs, K. et al. Adenohypophyseal tissue in an immature teratoma of the human ovary. Endocr Pathol 4, 48–52 (1993). https://doi.org/10.1007/BF02914489
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DOI: https://doi.org/10.1007/BF02914489