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Brain type natriuretic peptide (BNP)—A marker of new millennium in diagnosis of congestive heart failure

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Abstract

The burden of disease in patients with congestive heart failure is high. The future of BNP looks promising as it may be a better diagnostic tool for the diagnosis of CHF in developing countries in new millennium. Natriuretic peptide hormones, a family of vasoactive peptides with many favourable physiological properties, have emerged as important contenders for development of diagnostic tools and therapeutic agents in cardiovascular disease. Measurement of B-type natriuretic peptide has become as an easy-to-perform bedside test. The clinical and diagnostic significance of the measurement of plasma Nt-proBNP in the diseases of the cardiovascular system with particular emphasis on the assessment of patients with heart failure and their effects on predicting survival rate. The plasma levels of Nt-proBrain Natriuretic peptide responds more vigorously after myocardial infarction than those of other natriuretic peptides. This article is an attempt to give a short overview on the utility of BNP-blood levels for the diagnosis and treatment of heart failure

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Authors and Affiliations

  1. Department of Biochemistry, People's College of Dental Sciences & Research Centre, 462018, Bhopal

    Muzaiyan Ahmed Khan

  2. Department of Pathology, Hindu Rao Hospital, 110007, Delhi

    Harsh Vardhan Singh

  3. Department of Biochemistry, G. R. Medical College, 474002, Gwalior

    Neelima Singh

  4. Department of Clinical Biochemistry and Cardiology, Escorts Heart Insitute & Research Centre, 110025, New Delhi

    Arun Raizada, Suman Bhandari, Sherin Thomas, Vikram Sarabhai & Naresh Trehan

Authors
  1. Arun Raizada
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  2. Suman Bhandari
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  3. Muzaiyan Ahmed Khan
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  4. Harsh Vardhan Singh
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  5. Sherin Thomas
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  6. Vikram Sarabhai
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  7. Neelima Singh
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  8. Naresh Trehan
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Correspondence to Arun Raizada.

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Raizada, A., Bhandari, S., Khan, M.A. et al. Brain type natriuretic peptide (BNP)—A marker of new millennium in diagnosis of congestive heart failure. Indian J Clin Biochem 22, 4–9 (2007). https://doi.org/10.1007/BF02912873

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