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Transmission electron microscopic observation of CFU-Mix culture in normal adults and leukemia patients

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Summary

By use of transmission electron microscope we demonstrated that the limiting dilution assay is an important method for investigating differentiation of hemopoietic cells in vitro. If various growth factors were added into this culture system, the stem cells of normal adults could differentiate into erythrocyte, granulocyte, megakaryocyte and macrophage, while leukemic progenitor cells could not. The colony forming cell in leukemia still had the nature of leukemic cell.

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References

  1. 1987;10 200–3.

  2. I. 1981; 2 : 6–9.

  3. I. 1981; 2:170–2.

  4. 1988; 9 : 527–9.

  5. 1985 : 117–8.

  6. Messner NA, et al. Biology of acute myeloid leukemia. Clin Hematol 1986; 15:641–67.

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Authors and Affiliations

  1. Institute of Hematology, Tongji Medical University, Wuhan

    Chen Yan, Wang Bian-ming, Li Chong-Yu & Yu Dong-jiao

  2. Department of Ultrastructural Pathology, Tongji Medical University, Wuhan

    Ruan You-bing

Authors
  1. Chen Yan
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  2. Wang Bian-ming
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  3. Li Chong-Yu
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  4. Yu Dong-jiao
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  5. Ruan You-bing
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Yan, C., Bian-ming, W., Chong-Yu, L. et al. Transmission electron microscopic observation of CFU-Mix culture in normal adults and leukemia patients. Journal of Tongji Medical University 10, 27–30 (1990). https://doi.org/10.1007/BF02909118

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  • DOI: https://doi.org/10.1007/BF02909118

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