Summary
The histogenesis and relationship of so-called ‘granulomatous thymoma’ to Hodgkin’s disease is still a matter of controversy. Three of these lesions were selected from 43 thymomas and their clinico-pathological patterns are described. Two cases were diagnosed as Hodgkin’s disease of the mediastinum because of the absence of epithelial structures of thymic origin. In one case, together with the morphological aspects of Hodgkin’s disease, we noticed epithelial structures indicating a primary neoplastic lesion in the thymus. Accordingly we conclude that the term ‘Hodgkin’s disease of the thymus’ must be limited only to those lesions of the mediastinum in which structures of thymic origin are present. Other mediastinal Hodgkin’s lesions, even in the presence of clinical, radiological and surgical evidence of thymic origin but in which it is not possible to observe such thymic structures, must be classified as Hodgkin’s disease localized to the anterior mediastinum.
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References
Bernatz P. E., Harrison E. G., Clagett O. T.: Thymoma: Clinicopathologic Study — J. thorac. Surg.42, 424, 1961.
Castleman B.: Tumors of the Thymus Gland — In: Atlas of Tumor Pathology. Armed Forces Institutes of Pathology, Washington, D.C., 1955; sect. 5, issue no. 19.
Ewing J.: The Thymus and Its Tumors. Report of Three Cases of Thymoma — Surg. Gynec. Obstet.22, 461, 1916.
Fechner R. E.: Hodgkin’s Disease of the Thymus — Cancer23, 16, 1969.
Galy P., Renault P.: Formes anatomiques des tumeurs du thymus chez l’adulte — In: XXXVII Congrès Français de Médecine. Masson et Cie, Paris, 1969; p. 43.
Holmes-Sellors T., Thackeray A. C., Thomson A. D.: Tumours of the Thymus: A Review of 88 Operation Cases — Thorax22, 193, 1967.
Katz A., Lattes R.: Granulomatous Thymoma or Hodgkin’s Disease of the Thymus — Cancer23, 1, 1969.
Lattes R.: Thymoma and Other Tumors of the Thymus. An Analysis of 107 Cases — Cancer15, 1224, 1962.
Legg M. A., Brady M. J.: Pathology and Clinical Behaviour of Thymomas. A Survey of 51 Cases — Cancer18, 1131, 1965.
Lowenhaupt E., Brown R.: Carcinoma of the Thymus of Granulomatous Type. Clinical and Pathological Study — Cancer4, 1193, 1951.
Lukes R. J., Carver L. F., Hall T. C., Rappaport H., Ruben P.: Report of the Nomenclature Committee from Symposium on Obstacles to the Control of Hodgkin’s Disease — Cancer Res.26, 1311, 1966.
Marshall A. H. E., Wood C.: The Involvement of the Thymus in Hodgkin’s Disease — J. Path. Bact.73, 163, 1957.
Miller D. G.: Immunological Deficiency and Malignant Lymphoma — Cancer20, 579, 1967.
Patey D. H.: A Contribution to the Study of Hodgkin’s Disease — Brit. J. Surg.50, 389, 1963.
Roujeau J., Toty L., Beauchant G.: Thymome pseudohodgkinien — J. franç. Méd. Chir. thor.18, 519, 1964.
Thomson A. D.: Thymic Origin of Hodgkin’s Disease — Brit. J. Cancer9, 37, 1955.
Thomson A. D., Thackeray A. C.: Histology of Tumours of Thymus — Brit. J. Cancer11, 348, 1957.
Witz J. P., Miech G., Delage J., Reys Ph., Morand G.: Les tumeurs pseudogranulomateuses de la loge thymique — Ann. Chir. Thor. Car.6, 33, 1967.
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Ricci, C., Mineo, T.C. & Baroni, C.D. Hodgkin’s-like disease of the thymus. Clinical, surgical and morphological correlations. La Ricerca in Clin. Lab. 6, 23–29 (1976). https://doi.org/10.1007/BF02901486
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DOI: https://doi.org/10.1007/BF02901486