Abstract
The crystal structure of γ-hydroxy-β-aminobutyric acid was determined byMULTAN system with X-ray intensity data on a diffractometer and refined by the least-squares method to an Rvalue 0.034 for 711 reflections. The crystals were orthorhombic, space group P212121, Z=4, with a=10.220, b=8.257 and c=6.556Å. The molecule takes the zwitterionic form and skeletal conformation is trans-trans form. The molecules are held together by intra-and intermolecular NH---O and OH---O hydrogen bonds.
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Tomita, K., Fujiwara, T. and Harada, M.: Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids, and Their Derivatives. VI. Crystal and Molecular Structure of DL-γ-Amino-β-Hydroxybutyric Acid (GABOB), a Nervous Inhibitory Chemical Transmitter.Bull. Chem. Soc. Jpn. 46, 2854 (1973).
Tomita, K., Fujiwara, T. and Higashi, H.: Molecular Structure of ω-Amino Acids and ω-Aminosulfonic Acids.Jpn. Brain Physiol. 111, 111 (1971).
Main, P., Woolfson, M.M., Lessinger, L., Germain, G. and Delerco, J.P.:MULTAN 74. A System of Computer Programs for the Automatic Solution of Crystal Structures from X-ray Diffraction Data. Univs. of York, England and Louvainla-Neuve, Belgium
“International Tables for X-ray Crystallography”. Kynoch Press, England, Vol. IV, (1974).
Kim, Y.B., Wakahara, A., Fujiwara, T. and Tomita, K.: Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. III. The Crystal and Molecular Structure of γ-Guanidino-β-Hydroxypropane Sulfonic Acid.Bull. Chem. Soc. Jpn. 46, 2194 (1973).
Kim, Y.B., Wakahara, A., Fujiwara, T. and Tomita, K.: Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. V. Crystal and Molecular Structure of γ-Guanidino Propane Sulfonic Acid.Bull. Chem. Soc. Jpn. 46, 2543 (1973).
Sutherland, H.H. and Young, D.W.: The Crystal and Molecular Structure of Taurine.Acta Cryst.16, 897 (1963).
Okaya, Y.: Refinement of the Crystal Structure of Taurine, 2-Aminoethylsulfonic Acid, An Example of Computer-controlled Experimentation.Acta Cryst. 21, 726 (1966)
Ueoka, S., Fujiwara, T., and Tomita, K.: Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. II. The Crystal and Molecular Structure of α-Form of 3-Aminopropane Sulfonic Acid, Homotaurine.Bull. Chem. Soc. Jpn. 45, 3634 (1972).
Kim, Y.B., Bando, S., Hombo, T., Fujiwara, T., and Tomita, K.: Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. IX. Crystal and Molecular Structure of 3-Amino-2-Hydroxy-1-Propanesulfonic Acid.Bull. Chem. Soc. Jpn. 52, 2010 (1979).
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Kim, Y.B. The crystal and molecular structure of γ-hydroxy-β-amino butyric acid. Arch. Pharm. Res. 8, 1–6 (1985). https://doi.org/10.1007/BF02897559
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DOI: https://doi.org/10.1007/BF02897559