Summary
Serum anticardiolipin antibody (ACA) was measured in 91 patients with cerebral infarction (CI), 42 patients with cerebral hemorrhage (CH) and 30 healthy controls. The results showed that the ACA in CI and CH patients was significantly higher than in controls and IgG-ACA was the most important iso-type. Stroke in ACA positive group tended to be recurrent and of multi-focuses. Positive rate of IgG-ACA reached its peak within the first week after stroke on-set. The results suggested that ACA was an independent risk factor in CI and CH and might be valuable in stroke prediction.
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Montalban J, Rio J, Khamastha Met al. Value of immunologic testing in stroke patients. A prospective multicentre study. Stroke, 1994, 25:2412
ENA 1997, 10:18
1997, 5:331
Brey R L, Coull B M. Antiphospholipid antibodies: origin, specificity and mechanism of action. Stroke, 1992, 23(Suppl 1):15
Levine S R, Brey R L, Sawaya K Let al. Recurrent stroke and thrombo-occlusive event in the antiphospholipid syndrome. Ann Neurol, 1995, 38:119
Provenzale J M, Barboriak D P, Allen N Bet al. Patients with antiphospholipid antibodies: CT and MR findings of the brain. AJR, 1996, 167:1573
Muir K W, Squire I B, Alwan Wet al. ACA in an unselected stroke population. Lancet, 1994, 344:452
Kushner M J. Prospective study of anticardiolipin antibodies in stroke. Stroke, 1990, 21: 295
APASS Group. Anticardiolipin antibodies are independent risk factor for first ischemic stroke. Neurology, 1993, 43:2069
Camerlingo M, Casto L, Censori Bet al. Anticardiolipin antibodies in acute nonhemorrhagic stroke seen within six hours after stroke onset. Acta Neurol Scand, 1995, 92:69
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Changqin, L., Yun, X., Shenggang, S. et al. Study on relationship between anticardiolipin antibody and cerebrovascular diseases. Journal of Tongji Medical University 19, 59–62 (1999). https://doi.org/10.1007/BF02895599
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DOI: https://doi.org/10.1007/BF02895599