Summary
In the study of a tranplanted tumor, Sarcoma 180, the morphological features of the growing microvessels induced by tumor were observed electronmicroscopically at various times of tumor growth. It was found that microvessels in tumors could sprout by intracellular vacuolization or migration of endothelial cells, the former possibly resulting in saccular sprouts and the latter in tapering sprouts.
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Xiao-jun, Z., Yu-hui, X. & Zhong-bi, W. Ultrastructure of blood vessels newly formed during tumor angiogenesis. Journal of Tongji Medical University 8, 140–143 (1988). https://doi.org/10.1007/BF02887836
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DOI: https://doi.org/10.1007/BF02887836