Skip to main content
Log in

Bioinformatics, robust realm based upon multidisciplinary knowledge of biological data and computational techniques

  • Reviews
  • Published:
Chinese Science Bulletin

Abstract

The accumulation of the large amount of biological data concerning with gene and protein research has proposed that it is necessary to abstract the biological significance from these data. Then the bioinformatics, equipped with the most advanced computational techniques and supported by the latest biological research, has emerged for this purpose. Some recent information on the developing bioinformatics, associated with the uniform resource location addresses of those available resource sites that support hyper-text or general file transfer protocols on the Internet, from points like bioinformation databases of gene sequence or protein structure, general biocomputing softwares for genome analysis or protein structure analysis, online biocomputing servers dedicated for genomic database search or protein steric structure recognition and prediction, artificial life, etc. is reviewed. There are also other various approaches like Usenet, Newsgroup that focus on their specific topics introduced. Finally, the hottest problems and most gifted respects of the bioinformatics are discussed, whereas the bioinformatics has been regarded as an international cooperation in sciences, as well as a new challenge for life scientists in China.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Rodrigursz-Tome, P., The Bincatalog,Bioinformatics, 1998, 14(5): 469.

    Article  Google Scholar 

  2. Cooper, D. N., Ball, E.V., Krawczak, M., Thehuman gene mutation database,Nucleic Acids Res., 1998, 26(1): 285.

    Article  PubMed  CAS  Google Scholar 

  3. Sugawara. H., Miyazaki, S., Towards the Asia-Pacific Bioinfonnatics Network,Poc. Symp. Biocomput., 1998, (4): 759.

  4. Attwood, T. K., Beck, M. E., Uower, D. R.et al., The PRINTS protein fingerprint database in its fifth year,Nucleic Acids Res., 1998, 26(1): 304.

    Article  PubMed  CAS  Google Scholar 

  5. Bono, H., Ogata, H., Goto, S.et al., Reconstruction of amino acid biosynthrsis pathways from the complete genome sequencemGenome Res., 1998, 8(3): 203.

    PubMed  CAS  Google Scholar 

  6. Clemet, E., Coclani, J. J., LASSAP, a LArge Scale Sequence compArison Package,CABIOS, 1997. 13(2): 137.

    Google Scholar 

  7. Womiak, A., Using video oriented instructions to speed-up sequence comparison,CABIOS, 1997, 13(2): 145.

    Google Scholar 

  8. Proutski, V., Holmes, F., SWAN: sliding windows analysis of nucleotide srquenre variability,Bioinformatics, 1998, 14 (5): 467.

    Article  PubMed  CAS  Google Scholar 

  9. Trelles, O., Andrade, M. A., Valencia, A.et al., Computational space reduction and parallelization of a new clustering epproach for large groups of sequences,Bioinformatics, 1998, 14(5): 439.

    Article  PubMed  CAS  Google Scholar 

  10. Krause, A., Vingron, M., A set-theoretic approach to database searching and clustering,Bioinformatics, 1998, 14(5): 430.

    Article  PubMed  CAS  Google Scholar 

  11. Lijnzaad, P., Helgewn, C., Rodriguez-Tome, P., The Radiation Hybrid Database,Nucleic Acids Res., 1998, 26(1): 102.

    Article  PubMed  CAS  Google Scholar 

  12. Stoesser, G., Moseley, M. A., Sleep, J.et al., The EMBL nucleutide sequence database,Nucleic Acids Res., 1998, 26 (1): 8.

    Article  PubMed  CAS  Google Scholar 

  13. Van Ommen, G. J., The human genome project and the mle of genetics in health care,Clin. Chem. Lab. Med., 1998, 36 (8): 515.

    Article  PubMed  Google Scholar 

  14. Rebhan, M., Chalifa-Caspi, V., Prilusky, J.et al., GeneCards: a novel functional genomics cumpendium with automated data mining and query reformulation support,Bioinformatics, 1998, 14(8): 656.

    Article  PubMed  CAS  Google Scholar 

  15. Sorace, J. M., Canfield, K., Collaborative bioinformatics: data warehouses for targeted experimental results,J. Interferon Cytokine Res., 1998, 18(9): 799.

    Article  PubMed  CAS  Google Scholar 

  16. Borsani, G., Ballabio, A., Banfi, S., A practical guide to orient yourself in the labyrinth of genome databases,Hum. Mol. Genet., 1998, 7(10): 1641.

    Article  PubMed  CAS  Google Scholar 

  17. Goodman, N., Rozen, S., Stein, L. D.et al., The LabBase system for data management in large scale biology research laboratories,Bioinformatics, 1998, 14(7): 562.

    Article  PubMed  CAS  Google Scholar 

  18. Baxevanis, A. D., The Internet and the biologist,Methods Biochem Anal., 1998, 39: 1.

    Article  PubMed  CAS  Google Scholar 

  19. Gaasterland, T., Structural genomics: bioinformatirs in the driver’s seat,Nat Biotechnol., 1998, 16(7): 625.

    Article  PubMed  CAS  Google Scholar 

  20. Wu, C. H., Shivakumar, S., Shivakumar, C. V.et al., GeneFIND web server for protein family identification and information retrieval,Bioinformatics, 1998, 14(2): 223.

    Article  PubMed  CAS  Google Scholar 

  21. Kastin, S., Wexler, J., Bioinformatics: searching the Net,Semin. Nucl. Med., 1998, 28(2): 177.

    Article  PubMed  CAS  Google Scholar 

  22. Stein, L. D., Cartinhour, S., Thieny-Mieg, D.et al., JADE: an approach for interconnecting bioinformatics databases,Gene, 1998, 209(1-2): 39.

    Article  PubMed  Google Scholar 

  23. Baker, P. G., Brass, A., Recent developments in biological sequence databases,Curr. Opin. Biotechnol., 1998, 9(1): 54.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

About this article

Cite this article

Ouyang, S., He, F. Bioinformatics, robust realm based upon multidisciplinary knowledge of biological data and computational techniques. Chin. Sci. Bull. 44, 1825–1837 (1999). https://doi.org/10.1007/BF02886336

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02886336

Keywords

Navigation