Abstract
Biotransformation of dehydroepiandrosterone (I) and methylandrostenediol (VI) by means of the microorganismAbsidia orchidis yielded a mixture of epimeric 7-hydroxyderivatives II or VII. Microbial oxidation of these mixtures byFlavobacterium peregrinum afforded epimeric 7-hydroxyderivatives of 4-androsten-3,17-dione III and IV, or of methyltestosterone VIII and IX. The structure of these compounds was confirmed by partial synthesis.
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Schwarz, V., Protiva, J. Steroid derivatives. Folia Microbiol 19, 156–163 (1974). https://doi.org/10.1007/BF02872851
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DOI: https://doi.org/10.1007/BF02872851