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The inactivation ofBacillus subtilis transforming DNA by mutagenic agents

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Abstract

The inactivation of three genetic markers inBacillus subtilis transforming DNA by UV rays, nitrous acid and hydroxylamine was studied. The inactivation of markers by UV and HNO2 was marker specific, whereas the hydroxylamine inactivates the markers approximately to the same degree.

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References

  • Anagnastopoulos, C., Spizizen, J.:Requirements for transformation in Bacillus subtilis. J. Bacteriol. 81: 741, 1961.

    Google Scholar 

  • Burton, K.:The conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J. 62: 315, 1956.

    PubMed  CAS  Google Scholar 

  • Bautz-Freese, E., Freese, E.:Two separable effects of hydroxylamine on transforming DNA. Proc. nat. Acad. Sci. Wash. 52: 1289, 1964.

    Article  Google Scholar 

  • Litman, R. M., Ephrussi-Taylor, H.:Inactivation et mutation des facteurs génétiques de l'acide désoxyribonucléique du pneumocoque par l'ultraviolet et par l'acide nitreux. Compt. rend. Acad. Sci. 249: 838, 1959.

    CAS  Google Scholar 

  • Marmur, J.:A procedure for the isolation of deoxyribonucleic acid from microorganisms. J. mol. Biol. 3: 208, 1961.

    Article  CAS  Google Scholar 

  • Pivec, L., Šrogl, M., Zadražil, S., Fučík, V., Šormová Z.:Physical and biological properties of fractionated DNA from Bacillus subtilis. “The Physiology of Gene and Mutation Expression”. G. Mendel Memorial Symposium, Academia, Prague, 1965.

    Google Scholar 

  • Šrogl, M.:An attempt for determining the genetic relation in bacteria of the Bacillus subtilis group by means of transformation. Dissertation thesis, Czechoslovak Academy of Sciences, 1964.

  • Vielmetter, W., Schuster, H.:Die Basenspezifität bei der Induktion von Mutationen durch salpetrige Säure in Phagen T 2. Z. Naturforsch. 15b: 304, 1960.

    CAS  Google Scholar 

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Kapadia, R.T., Šrogl, M. The inactivation ofBacillus subtilis transforming DNA by mutagenic agents. Folia Microbiol 14, 51–53 (1969). https://doi.org/10.1007/BF02869399

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  • DOI: https://doi.org/10.1007/BF02869399

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