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A comparative study on the effects of Gemfibrozil, Diltiazem and Isosorbide dinitrate on lipid profile in patients of ischemic heart disease in India

  • Heart Diseases
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Abstract

Effects of three drugs, Gemfibrozil, Diltiazem and lsosorbide dinitrate (ISDN) on various lipid parameters were studied in patients with ischemic heart disease (IHD) with positive treadmill stress response. Gemfibrozil and diltiazem significantly lowered the levels of serum total lipids (TL), triglycerides (TG), phospholipids (PL), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C), and incroased the levels of serum high density lipoprotein cholesterol (HDL-C) significantly. However, patients administered with ISDN showed a significant increase in all the lipid parameters except HDL-C, which showed a significant decrease.

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Authors and Affiliations

  1. Upgraded Department of Medicine, S.M.S. Medical College, Jaipur, Rajasthan

    S. K. Sharma

  2. Department of Biochemistry, M.P. Shah Medical College, 361 008, Jamnagar, Gujarat

    H. O. Sharma (Assistant Professor)

Authors
  1. H. O. Sharma
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  2. S. K. Sharma
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Sharma, H.O., Sharma, S.K. A comparative study on the effects of Gemfibrozil, Diltiazem and Isosorbide dinitrate on lipid profile in patients of ischemic heart disease in India. Indian J Clin Biochem 12, 45–48 (1997). https://doi.org/10.1007/BF02867954

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  • DOI: https://doi.org/10.1007/BF02867954

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