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Steroid derivatives

XLVII. Microbial Transformation of 16β-Methyl-16,17-oxido-7β,11α-dihydroxypregn-4-ene-3,20-dione UsingMycobacterium flavum

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Abstract

Mycobacterium flavum was used to effect the transformation of 16β-methyl-16,17-oxido-7β,11α-dihydroxypregn-4-ene-3,20-dione (I) and the final products were isolated and identified as 16β-methyl-16,17-oxido-7β,11α-dihydroxypregna-1,4-diene-3,20-dione (II) and 16β-methyl-16,17-oxido-11α-hydroxypregna-1,4,6-triene-3,20-dione (IV), and the intermediate product as 16β-methyl-16,17-oxido-11α-hydroxypregna-4,6-diene-3,20-dione (III).

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Authors and Affiliations

  1. Research Institute for Natural Drugs, Prague 9

    J. Protiva, J. Martínková & V. Schwarz

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  1. J. Protiva
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  2. J. Martínková
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  3. V. Schwarz
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Protiva, J., Martínková, J. & Schwarz, V. Steroid derivatives. Folia Microbiol 13, 7–11 (1968). https://doi.org/10.1007/BF02866855

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  • DOI: https://doi.org/10.1007/BF02866855

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