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Screening of Korean medicinal plants for antitumor activity

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Abstract

Potential antitumor activity of sixteen Korean medicinal plants was tested against leukemia SN 36, murine tumor model. Survival studies by measuring life span indicated thatMorus alba (Moraceae), Verbascum phlomoides (Scrophulariaceae), Curcuma longa (Zingiberaceae), Torilis japonica (Umbelliferae), Bupleurum falcatum (Umbelliferae) andCodonopsis pilosula (Campanulaceae) exhibited significant antitumor activity with the dose-schedule employed in the experiment. Methanol(70%) extracts ofPlatycodon grandiftorum (Campanulaceae), Bupleurum longeradiatum (Umbelliferae) andAsiasarum sieboldii (Aristolochiaceae) showed rather potent toxicity.

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Literature Cited

  1. Woo, W. S., Shin, K. H. and Kwon, Y. M., Biological evaluation of Korean medicinal plants.J. Pharm. Soc. Korea 16, 121(1972).

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  2. Woo, W. S., Lee, E. B. and Chang, I. M., Biological evaluation of Korean medicinal plants II.J. Pharm. Soc. Korea 21, 177(1977).

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  3. Woo, W. S., Lee, E. B. and Han, B. H., Biological evaluation of Korean medicinal plants. III.Arch. Pharm. Res. 2, 127(1979).

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  1. Natural Products Research Institute, Seoul National University, 110, Seoul, Korea

    Il-Moo Chang & Won Sick Woo

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  1. Il-Moo Chang
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  2. Won Sick Woo
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Chang, IM., Woo, W.S. Screening of Korean medicinal plants for antitumor activity. Arch. Pharm. Res. 3, 75–78 (1980). https://doi.org/10.1007/BF02855806

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  • DOI: https://doi.org/10.1007/BF02855806

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