Dedicated monitoring of anesthetic and respiratory gases By Raman scattering

Abstract

The monitoring of respiratory and anesthetic gases in the operating room is important for patient safety. This study measured the accuracy and response time of a multiplegas monitoring instrument that uses Raman light scattering. Measurements of oxygen, carbon dioxide, nitrogen, nitrous oxide, halothane, enflurane, and isoflurane concentrations were compared with a gas mixer standard and with measurements made with an infrared anesthetic agent analyzer. Correlation coefficients were all greater than 0.999, and probable errors were less than 0.43 vol% for the gases and less than 0.03 vol% for the volatile anesthetics. Response time was 67 ms with a sample flow rate of 150 ml/min. There was some signal overlap between nitrogen and nitrous oxide and between the volatile anesthetic agents. Such overlap can be compensated for by linear matrix analysis. The Raman instrument promises a monitoring capability equivalent to the mass spectrometer and should prove attractive for the monitoring of respiratory and anesthetic gases in the operating room.

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Correspondence to Dwayne R. Westenskow PhD.

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Van Wagenen, R.A., Westenskow, D.R., Benner, R.E. et al. Dedicated monitoring of anesthetic and respiratory gases By Raman scattering. J Clin Monitor Comput 2, 215–222 (1986). https://doi.org/10.1007/BF02851168

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Key Words

  • Monitoring: anesthetic gas
  • respiratory gas
  • Measurement techniques: Raman light scattering
  • Equipment: gas analyzers
  • sensors, oxygen
  • carbon dioxide
  • nitrous oxide
  • nitrogen
  • anesthetic agent