Abstract
The synthesis and characterization of a series of metal porphyrins, MII(Por), {Por=dianionic of 5, 10, 15, 20-tetrakis [4-(4′-bromobutyloxy) phenyl]porphyrinato and 5, 10, 15, 20-tetrakis [4-(4′-butyloxypyridine bromide)phenyl]porphyrinato, M=Zn, Cu, Mn, Co, Ni, Ru-CO} were described. The complexes 3a-3e were prepared from the reactions of compound 2 with metal acetates in chloroform, and the treatment of 3a-3f with excess of pyridine gave corresponding complexes 4a-4f. These new compounds were identified by absorption spectroscopies,1H-NMR and elemental analyses. The results of biological activity testing for 4a-4f revealed that 4a and 4c had stronger inhibiting action on the growth metabolism ofEsche richia coli.
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Foundation item: Supported by the National Natural Science Foundation of China (No: 29972035) and the Zi-Qiang Science Foundation of Wuhan University, 2000
Biography: Li Zao-ying (1949-), famale, Professor, research interests, study on synthesis and biological activities of metalloprphrins.
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Zao-ying, L., Yue-ning, Z., Wei, X. et al. Study on synthesis and biological activities of novel water-soluble metalloporphyrins. Wuhan Univ. J. Nat. Sci. 6, 841–845 (2001). https://doi.org/10.1007/BF02850915
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DOI: https://doi.org/10.1007/BF02850915