Abstract
It is confirmed that the essential condition for glasses and glass-ceramics to bond to living bone is the formation of an apatite layer on their surfaces in the body. It is proposed that a hydrated silica formed on the surfaces of these materials in the body plays an important role in forming the surface apatite layer, which has noi been proved yet. It is shown experimentally that a pure hydrated silica gel can induce the apatite formation on its surface in a simulated body fluid when its starting pH is increased from 7.2 to 7.4.
Similar content being viewed by others
References
Grizzi I, Garreau H,et al. Hydrolytic Degradation of Devices Based on Poly (DL—Lactic Acid) Size-dependence.Biomaterials, 1995, 16(4): 305–311.
K Ohura and T Yamamuro. Bone-bonding Ability of P2O5—Free CaO·SiO2 Glasses.J. Biomed. Mater. Res., 1991, 25(3): 357–365
Matsusue Y, Hanafuse S,et al. Tissue Reaction of Bioabsorbable Ultra-high-strength Poly (L-Lactide) Rod.Clin Orthop, 1995, 317: 246–253.
Cuneyt A T, Korkusuz F,et al. An Investigation of HA and TCP Bioceramics with Control of Their Strength and Phase Purity.J. Mater. Sci. Mater. Med., 1997, 8: 29–37.
T Yamamuro and T Kitsugi. Replacement of the Lumbar Vertebrae of Sheep with Ceramic Prostheses.J. Bone Surg., 1999, 72 (5): 889–893.
Author information
Authors and Affiliations
Additional information
FAN Dong-hui: Born in 1965.
Rights and permissions
About this article
Cite this article
Dong-hui, F., Zheng, X., Shi-pu, L. et al. Formation of apatite in simulated body fluid. J. Wuhan Univ. Technol.-Mat. Sci. Edit. 17, 44–46 (2002). https://doi.org/10.1007/BF02838415
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02838415