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Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction

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Abstract

Objective: To study the effects of Dachengqi Tang (DCQT) granule on the proliferation of the intestinal epithelial cells in rats with experimental intestinal obstruction.Methods: Experimental intestinal obstruction models were established in rats and autoradiography with3 H-TdR was used to determine3H-TdR labeling counts of intestinal epithelial cells in rats.Results: DCQT granule had no effects on3H-TdR labeling counts of intestinal epithelial cells in normal rats. DCQT granule obviously increases the rate of renovation in intestinal epithelial cells of the intestinal obstruction rats.Conclusion: DCQT granule could reinforce the intestinal mucosa’s defensive function by means of increasing the proliferation of intestinal epithelial cells.

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Authors and Affiliations

  1. Department of Pharmacology, Tianjin Medical University, 300070, Tianjin

    Kang Yi & Lin Xiu-zhen

Authors
  1. Kang Yi
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  2. Lin Xiu-zhen
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This project was supported by the State’s Key Projects of the Tenth Five-year Plan (No. 969030105)

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Yi, K., Xiu-zhen, L. Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction. Chin. J. Integr. Med. 9, 57–59 (2003). https://doi.org/10.1007/BF02836359

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  • DOI: https://doi.org/10.1007/BF02836359

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