Abstract
A modified PTC method of preparing tetra-O-alkylated calix[4]arenes is described. Using PEG-400 as phase-transfer catalyst and solid sodium hydrate as a base, full alkylation of calix[4]arenes has been proceeded smoothly in toluene at 90°C. The debutylated calix[4]arene can also be fully alkylated by this method.
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Supported by the National Natural Science Foundation of China
Hu Xubo: born in 1965, Ph. D. Graduate student
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Xubo, H., Yinyin, C., Heping, D. et al. Synthesis of tetra-O-alkylated calix[4]arenes under phase-transfer conditions. Wuhan Univ. J. Nat. Sci. 3, 214–216 (1998). https://doi.org/10.1007/BF02827555
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DOI: https://doi.org/10.1007/BF02827555