Abstract
Incubation of ampicillin with whole cells ofStreptomyces sp. DRS-1 resulted in accumulation of four compounds different from ampicillin. One of them was isolated, purified and partially characterized. On the basis of spectroscopic characteristics,R F value and antibacterial activity the compound was identified as cephalexin. It could also be obtained from ampicillin by using crude protein extract of the strain.
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Roy, D., Sharma, A., Bhowmick, G. et al. Characterization ofStreptomyces sp. Strain DRS-1 and its ampicillin transformation product. Folia Microbiol 42, 333–336 (1997). https://doi.org/10.1007/BF02816945
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DOI: https://doi.org/10.1007/BF02816945