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Immunoenzymatic determination of antibody-bound soluble antigens ofTrypanosoma cruzi

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Abstract

Anti-Major Cathodic Antigen (MCA) monospecific immunoglobulins ofT. cruzi have been used for the preparation of polyamide-linked immunoadsorbents. A high proportion of serologically positive patients with Chagas disease show the presence of a soluble antigen complexed with human immunoglobulins, which complex binds to those immunoadsorbents as determined by a double sandwich reaction and a peroxidase final determination.

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Marcipar, A., Barnes, S., Lentwojt, E. et al. Immunoenzymatic determination of antibody-bound soluble antigens ofTrypanosoma cruzi . Appl Biochem Biotechnol 7, 459–462 (1982). https://doi.org/10.1007/BF02799177

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  • DOI: https://doi.org/10.1007/BF02799177

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