Abstract
It is known that a large quantity of magnesium contains bones, and the magnesium contents in spongy bones decrease gradually with advancing age. To elucidate the relationships between a decrease of mineral contents in human bones and an accumulation of minerals in the other human tissues, the content of magnesium was analyzed by inductively coupled plasma-atomic emission spectrometry among human bones, arteries, veins, and cartilages in 27 subjects (17 men and 10 women). These were resected from the subjects who died in the age range 40–98 yr. Calcanei were chosen for analysis of magnesium contents in contrast with femoral, popliteal, and common carotid arteries, internal jugular and femoral veins, superior and inferior venae cavae, and pubic symphyses.
The magnesium contents in the calcanei decreased gradually with aging, whereas they increased progressively in the arteries, veins, and pubic symphyses with aging. It was found that as the magnesium contents decreased in the calcanei, they increased in the arteries, such as the femoral, popliteal, and common carotid arteries, whereas they decreased inversely in the veins, such as the internal jugular and femoral veins and superior and inferior venae cavae. Furthermore, as the magnesium contents decreased in the calcanei, they hardly changed in the pubic symphyses. These suggest that magnesium released from bones is accompanied by accumulation of magnesium in the arteries.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Y. Tohno, S. Tohno, T. Minami, M. Ichii, Y. Okazaki, M. Utsumi, et al., Age-related changes of mineral contents in human thoracic aorta and in the cerebral artery,Biol. Trace Element Res. 54, 23–31 (1996).
T. Araki and Y. Tohno, Age dependency of nanosecond fluorescence characteristics in human artery,Front. Med. Biol. Eng. 7, 265–273 (1996).
T. Minami, M. Ichii, Y. Tohno, S. Tohno, M. Utsumi, M.-o. Yamada, et al., Age- dependent aluminum accumulation in the aorta and cerebral artery,Biol. Trace Ele- ment Res. 55, 199–205 (1996).
S. Tohno, Y. Tohno, T. Minami, Y. Okazaki, M. Utsumi, F. Nishiwaki, et al., High accumulation of elements in the human femoral artery,Biol. Trace Element Res. 57, 27–37 (1997).
S. Tohno, Y. Tohno, T. Minami, Y. Okazaki, M. Utsumi, F. Nishiwaki, et al., Differen- tial accumulation of calcium and phosphorus in the human arteries,Acta Anat. Nip- pon. 72, 451–454 (1997).
Y Tohno, S. Tohno, T. Minami, M. Utsumi, Y. Moriwake, F. Nishiwaki, et al., Age- related changes of mineral contents in the human aorta and internal thoracic artery,Biol. Trace Element Res. 61, 219–226 (1998).
S. Tohno and Y. Tohno, Age-related differences in calcium accumulation in human arteries,Cell. Mol. Biol. 44, 1253–1263 (1998).
S. Tohno, Y Tohno, T. Minami, Y. Okazaki, M. Utsumi, F. Nishiwaki, et al., A high accumulation of minerals in human internal jugular vein,Biol. Trace Element Res. 62, 17–23 (1998).
Y. Tohno, S. Tohno, M. Utsumi, T. Minami, M. Ichii, Y Okazaki, et al., Age- independent constancy of mineral contents in human vertebrae and auditory ossi- cles,Biol. Trace Element Res. 59, 167–175 (1997).
Y Tohno, M. Utsumi, S. Tohno, T. Minami, Y Okazaki, Y Moriwake, et al., Age- dependent changes of mineral contents in man’s and woman’s calcanei,Biol. Trace Element Res. 60, 81–90 (1997).
Y. Tohno, M. Utsumi, S. Tohno, T. Minami, Y. Okazaki, Y Moriwake, et al., A constancy of mineral contents in human auditory ossicles,Acta Anat. Nippon. 72, 531–534 (1997).
M. Utsumi, S. Tohno, T. Minami, Y. Okazaki, Y. Moriwake, M.-o. Yamada, et al., Age- independent constancy of mineral contents in human ribs,Biol. Trace Element Res. 67, 165–171 (1999).
S. Tohno, Y. Tohno, T. Minami, M. Ichii, Y Okazaki, M. Utsumi, et al., Difference of mineral contents in human intervertebral disks and its age-related change,Biol. Trace Element Res. 52, 117–124 (1996).
S. Tohno, Y Tohno, T. Minami, Y Okazaki, M. Utsumi, Y Moriwake, et al., High accu- mulations of calcium and phosphorus in woman’s pubic symphysis,Biol. Trace Ele- ment Res. 59, 177–185 (1997).
Y. Moriwake, Y. Tohno, S. Tohno, T. Minami, M. Utsumi, F. Nishiwaki, et al., Age- related changes of element contents in the human meniscus,Biol. Trace Element Res. 64, 229–235 (1998).
Y. Takano, Y. Moriwake, Y. Tohno, T. Minami, S. Tohno, M. Utsumi, et al., Age-related changes of elements in the human articular disk of temporomandibular joint,Biol. Trace Element Res. 67, 269–276 (1999).
R. M. Touyz, F. J. Milne, and S. G. Reinach, Platelet and erythrocyte Mg2+, Ca2+, Na+, K+, and cell membrane adenosine triphosphatase activity in essential hypertension in blacks,J. Hypertens. 10, 571–578 (1992).
Y. Tohno, S. Tohno, H. Matsumoto, and K. Naito, A trial of introducing soft X-ray apparatus into dissection practice for students [in Japanese],J. Nara Med. Assoc. 36, 365–370 (1985).
F. Burny and R. Wollast, Study of bone mineralization at the microscopic level using the electron probe microanalyser. Sodium and magnesium distribution in normal bone,Acta Orthoped. Belg. 38, 79–84 (1972).
S. Tsuboi, H. Nakagaki, K. Ishiguro, K. Kondo, M. Mukai, C. Robinson, et al., Mag- nesium distribution in human bone,Calcif. Tissue Int. 54, 34–37 (1994).
W. S. Watson, T. D. B. Lyon, and T. E. Hilditch, Red cell magnesium as a function of cell age,Metabolism 29, 397–399 (1980).
Y. Tohno, S. Tohno, T. Minami, Y. Moriwake, M. Utsumi, F. Nishiwaki, et al., A pos- sible balance of calcium accumulations among bone, cartilage, artery, and vein in sin- gle human individuals,Biol. Trace Element Res. 63, 105–111 (1998).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tohno, S., Tohno, Y., Masuda, M. et al. A possible balance of magnesium accumulations among bone, cartilage, artery, and vein in single human individuals. Biol Trace Elem Res 70, 233–241 (1999). https://doi.org/10.1007/BF02783832
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02783832