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Monitoring of cephalosporin C during bioconversion

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Abstract

A simple method based on Schiff’s base formation betweenp-dimethylaminobenzaldehyde and cephalosporin C is developed for estimation of cephalosporin C. The calibration curve was linear up to 500 μg of cephalosporin C. The application of the method in monitoring bioconversion of cephalosporin C to glutaryl-7-amino cephalosporanic acid is described.

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Authors and Affiliations

  1. Research and Development, Hindustan Antibiotics Limited, Pimpri, 411018, Pune, India

    Bhagwant S. Despande, Sudha S. Ambedkar & Jaiprakash G. Shewale

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  1. Bhagwant S. Despande
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  2. Sudha S. Ambedkar
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  3. Jaiprakash G. Shewale
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Despande, B.S., Ambedkar, S.S. & Shewale, J.G. Monitoring of cephalosporin C during bioconversion. Appl Biochem Biotechnol 60, 245–250 (1996). https://doi.org/10.1007/BF02783587

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  • DOI: https://doi.org/10.1007/BF02783587

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