Summary
Progression of acute non-A, non-B (NANB) posttransfusion hepatitis to liver cirrhosis has been well recognized as in hepatitis B infection, whereas no progression of acute NANB sporadic hepatitis to liver cirrhosis has yet been documented.
We reported a 29-year-old male with prolonged transaminase elevations in whom acute NANB sporadic hepatitis progressed to histologically confirmed cirrhosis during follow-up of about 3 years.
It is suggested that some of the cryptogenic cirrhosis of non-B type may develop from acute NANB sporadic hepatitis and long-term observation is also needed in patients with acute hepatitis of this category.
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Nagata, A., Kiyosawa, K., Akahane, Y. et al. A case of acute non-A, non-B sporadic hepatitis with evolution of liver cirrhosis on serial histologic follow-up. Gastroenterol Jpn 17, 591–595 (1982). https://doi.org/10.1007/BF02779137
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DOI: https://doi.org/10.1007/BF02779137