Summary
For the purpose of elucidating the motility, particularly the mechanism of contraction of the gallbladder, we classified gallbladders isolated surgically into three groups for a study. That is, the three groups comprised Group I of 40 cases of cholelithiasis with good contraction, Group II of 10 cases of cholelithiasis with poor contraction and Group III of 10 cases of cholelithiasis after gastrectomy for a total of 60 cases. Using gallbladders of these cases, we started with a fundamental study on the autonomic nervous action by the fluorescence histochemical method of Flack and Hillarp and obtained results as follows.
Similar results were obtained for Group I and Group II; the gallbladder was subjected to adrenergic innervation and cholinergic innervation, and there was a clear localized difference between true-cholinesterase and pseudo-cholinesterase of the cholinergic nerve. In Group III, proliferation of adrenergic nerve was observed compared with Groups I and II, while disappearance of cholinergic nerve was seen. The gallbladder of Group HI showed slight contraction with cholecystokinin, but it was not blocked with atropine.
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Tsurumi, K., Onda, M. A Fluorescence histochemical study for the motility of the gallbladder. Gastroenterol Jpn 14, 147–152 (1979). https://doi.org/10.1007/BF02773587
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DOI: https://doi.org/10.1007/BF02773587