Abstract
Phosphatidylcholine liposomes normalize phosphatidylcholine and lysophospholipid levels in mitochondrial membranes of the medulla oblongata of cats with hemorrhagic shock. In the frontal lobes of brain hemispheres of liposome-treated cats, phospholipid levels in the mitochondria and their membranes are close to the norm, with the exception of phosphatidylserine and lysophosphatidylserine: their contents in the inner mitochondrial membranes remain below the control. It is concluded that phosphatidylcholine liposomes exert protect brain mitochondrial membranes in hemorrhagic shock.
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Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 4, pp. 374–377, April, 1997
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Leskova, G.F., Udovichenko, V.I. Use of phosphatidylcholine liposomes for correction of mitochondrial phospholipid composition in the medulla oblongata and frontal lobes in hemorrhagic shock. Bull Exp Biol Med 123, 322–325 (1997). https://doi.org/10.1007/BF02766176
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DOI: https://doi.org/10.1007/BF02766176