Summary
Seventy eight paired sera were studied for sero-conversion after oral polio vaccine, in children belonging to the age group 3 months to 3 years. Sero-conversion was highest i.e. 92 3 percent for polio virus 2, 83.3 percent for polio virus 3 and 57.6 per cent for polio virus. The number of triple negative children was reduced to 2.6 per cent from 46.1 per cent after giving 3 doses of oral polio vaccine.
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Arumanayagam, P., Mendis, N.M.P. (1965). Outbreak of poliomyelitis in Ceylon in 1962.Am. J. Trop. Med. Hyg. 14, 440.
Bodian, D. (1965). Poliovirus in chimpanzee tissues after virus feeding.Am. J. Hyg. 64, 181.
Chaudhary, D.S., Nonik, N.N., Vijayan, Bindu, Raghaban, N.G.S., Paul, S. (1973). Poliomyelitis vaccination of infants, perimmunization status and serocon version.Bull. WHO 48, 195.
Domok, I.M.S., Balayan, O.A., Fayinka, N., Skrtic, Soneji, A.D., Herland, P.S.E.G. (1974). Factors affecting the efficacy of live polio virus vaccine in warm climates.Bull. WHO 51, 333.
Drozdov, S.G., Cockburn, W.C. (1971). Pohomyelitis in the developed and developing countries. Pan American Health Organization, 163–170. (Scientific Publication No. 226).
Franklin, G.C., Robertson, M.J. (1965). A mass vaccination campaign against poliomyelitis using the Sabin oral vaccine.Public Health (London) 79, 81.
Ghosh, S., Kumari, S., Balaya, S. (1970). Antibody response to oral polio vaccine in infancy.Indian Pediatr. 7, 78.
Hardas, V.D., Waiker, A.S. (1974). Pilot, survey of disabled children in and around Nagpur.Indian J. Pediatr. 41, 276.
Horstmann, D.M., Paul, J.R., McCrea, Godenne, (1961). Immunization of preschool children with oral vaccine (Sabin).JAMA 178, 693.
John, T.J., Devarajan, L.V., Balasubramanyan, A. (1976). Immunization in India with trivalent and monovalent oral poliovirus vaccine of enhanced potency.Bull WHO,54, 115.
John, T.J., Devarajan, L.V., Luthers L., Vijayarathnam, P. (1976). Effect of breast feeding on seroresponse of infants to oral poliovirus vaccination.Pediatrics 57, 47.
John, T., Javabal, P. (1972). Oral polio vaccination of children in the tropics.Am. J. Epidem. 96, 263.
Lee, L.H., Limk, A., Tye, C.Y. (1964). Prevention of poliomyelitis in Singapore by live vaccine.B.M.J. 1, 1077.
Montefiore, D.G., Jamioson, M.F., Collard, P., Hugh, Jolly. (1963). Trial of type 1 oral polio vaccine (Sabin) in Nigerian children.Brit. Med. J. 2, 1569.
Nategh, R. (1970). Mass trivalent oral polio vaccination in primary school age children in Teheran.Trop. Geog. Med. 22, 303.
Ogra, P.L., Karzon, P.J., Righthand, F., Mac-Gillivray, M. (1963). Immunoglobulin with live and inactivated polio vaccine and natural infection.New Eng. J. Med. 279.
Poliomyelitis Commission of the Western Region, Munistry of Health, Nigeria. (1966). Poliomyelitis vaccination in Ibadan, Nigeria, during 1964 with oral vaccine (Sabin strain).Bull WHO,34, 865.
Sangkawibha, N. (1969). Antibody response and virus excretion after oral vaccination with trivalent live poliomyelitis vaccine.J. Med. Asso. Thailand,52, 701.
Witte, J.J., Page, M.I., Gelfand, H.M. (1965). Control of type I epidemic in British Guiana.Bull. W.H.O. 33, 1.
Youngner, J.S. (1959). Monolayer tissue culture.Proc. Soc. Exper. Biol. & Med. 85, 202.
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From the Department of Microbiology, Medical College, Nagpur.
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Hardas, U.D., Pathak, A.A. & Jahagirdar, V.L. Sero-conversion after oral polio vaccine. Indian J Pediatr 45, 310–313 (1978). https://doi.org/10.1007/BF02749258
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DOI: https://doi.org/10.1007/BF02749258