Abstract
A generally healthy office working population (N = 644) was investigated using eight pulmonary function indices obtained from maximum expiratory flow volume curves and single breath nitrogen/closing volume tests. Abnormal test results were related to smoking history. Results showed a) increases in pulmonary dysfunction among current smokers on most tests, b) delta nitrogen as the test most sensitive to smoking effects, and c) some reversal of smoking-related dysfunction in exsmokers. These findings may have implications in the early detection of chronic obstructive lung disease.
Similar content being viewed by others
References
Bates, D.V.: The prevention of emphysema. Chest65, 437–441 (1974)
Bode, F.R., Dosman, J., Martin, R.R., and Macklem, P.T.: Reversibility of pulmonary function abnormalities in smokers. Amer. J. Med.59, 43–52 (1975)
Buist, A.S., Ross, B.B.: Predicted values for closing volumes using a modified single breath nitrogen test. Amer. Rev. Respir. Dis.107, 744–752 (1973)
Buist, A.S., Van Fleet, D.L., Ross, B.B.: Comparison of conventional spirometric tests and the test of closing volume in an emphysema screening center. Amer. Rev. Respir. Dis.107, 735–743 (1973)
Buist, A.S., Sexton, G.J., Nagy, J.M., Ross, B.B.: Effect of smoking cessation and modification on lung function. Amer. Rev. Respir. Dis.114, 115–122 (1976)
Grimes, C.A., Hanes, B.: Influence of cigarette smoking on the spirometric evaluation of employees of a large insurance company. Amer. Rev. Respir. Dis.108, 273–282 (1973)
Afifi, A.A., Azen, S.P.: Statistical Analysis: A Computer Oriented Approach. New York: Academic Press 1972
Macklem, P.T.: Obstruction in small airways: A challenge to medicine. Amer. J. Med.52, 721–722 (1972)
McCarthy, D.S., Craig, D.B., Cherniack, R.M.: Effect of modification of the smoking habit on lung function. Amer. Rev. Respir. Dis. 114, 103–114 (1976)
Niewoehner, D.E., Kleinerman, J., Rice, D.B.: Pathologic changes in peripheral airways of young cigarette smokers. New Engl. J. Med.291, 755–758 (1974)
Author information
Authors and Affiliations
Additional information
Research supported by NHLI contract NOL-HR3-2901 and NHLI Specialized Center of Research (SCOR) Grant No. HL-15098.
Associate Professor of Community Medicine and Public Health and Biomedical Engineering.
Rights and permissions
About this article
Cite this article
Azen, S.P., Linn, W.S., Hackney, J.D. et al. A comparison of eight lung function indices in smoking and non-smoking office workers. Lung 154, 213–221 (1976). https://doi.org/10.1007/BF02713536
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02713536