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Lipid peroxidation of hyperlipemic rat serum lipoproteins in chronic ethanol and acetaldehyde administration

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Abstract

The levels of lipid peroxides in circulatory lipoproteins increased with chronic administration of ethanol or acetaldehyde. Low density lipoprotein showed a greater increase in its content of lipid peroxides than very low density lipoprotein or high density lipoprotein. However, very low density lipoprotein was more prone to lipid peroxidationin vitro than low density lipoprotein or high density lipoprotein. The effect of acetaldehyde was more marked than that of ethanol. Lipoproteins of control and hyperlipemic groups were partially protected against peroxidation by butyrated hydroxytoluene and serum high density lipoprotein of normal rats.

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Abbreviations

LPO:

Lipid peroxide

VLDL:

very low density lipoprotein

LDL:

low density lipoprotein

HDL:

high density lipoprotein

BHT:

butyrated hydroxytoluene

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Chander, R., Kapoor, N.K. & Singh, C. Lipid peroxidation of hyperlipemic rat serum lipoproteins in chronic ethanol and acetaldehyde administration. J Biosci 13, 269–274 (1988). https://doi.org/10.1007/BF02712151

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  • DOI: https://doi.org/10.1007/BF02712151

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