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Effect of amitriptyline on daily variations in cell composition of immune organs in rats with experimental desynchronosis

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Abstract

We studied the effects of amitriptyline (preparation stimulating melatonin synthesis in the pineal gland) on daily variations of cell composition in immune organs of Wistar rats with experimental desynchronosis. Amitriptyline administered in the evening restored the daily dynamics of the number of thymus cells.

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Authors and Affiliations

  1. Institute of Clinical and Experimental Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk

    G. I. Litvinenko, L. V. Verbitskaya, L. V. Taradanova, E. V. Mel’nikova, M. V. Tenditnik & A. V. Shurlygina

  2. Siberian Division of the Russian Academy of Medical Sciences, Institute of Physiology, Novosibirsk

    V. A. Trufakin

Authors
  1. G. I. Litvinenko
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  2. L. V. Verbitskaya
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  3. L. V. Taradanova
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  4. E. V. Mel’nikova
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  5. M. V. Tenditnik
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  6. A. V. Shurlygina
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  7. V. A. Trufakin
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Corresponding author

Correspondence to A. V. Shurlygina.

Additional information

Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 130, No. 11, pp. 589–592, November, 2000

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Litvinenko, G.I., Verbitskaya, L.V., Taradanova, L.V. et al. Effect of amitriptyline on daily variations in cell composition of immune organs in rats with experimental desynchronosis. Bull Exp Biol Med 130, 1120–1122 (2000). https://doi.org/10.1007/BF02688196

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  • DOI: https://doi.org/10.1007/BF02688196

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