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Intestinal innate immunity and the pathogenesis of Salmonella enteritis

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Abstract

Acute gastroenteritis caused by Salmonella typhimurium infection is a clinical problem with significant public health impact. The availability of several experimental models of this condition has allowed detailed investigation of the cellular and molecular interactions involved in its pathogenesis. Such studies have shed light on the roles played by bacterial virulence factors and host innate immune mechanisms in the development of intestinal inflammation.

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  1. Bobby J. Cherayil

    Present address: Mucosal Immunology Laboratory, Division of Pediatric Gastroenterology and Nutrition, Room 3400, Massachusetts General Hospital, East Building 114, 16th Street, 02129, Charlestown, MA

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  1. Harvard Medical School, 02129, Charlestown, MA

    Chittur V. Srikanth & Bobby J. Cherayil

  2. Mucosal Immunology Laboratory, Division of Pediatric Gastroenterology and Nutrition, Room 3400, Massachusetts General Hospital, East Building 114, 16th Street, 02129, Charlestown, MA

    Chittur V. Srikanth

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Srikanth, C.V., Cherayil, B.J. Intestinal innate immunity and the pathogenesis of Salmonella enteritis. Immunol Res 37, 61–77 (2007). https://doi.org/10.1007/BF02686090

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