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Effects of haloperidol, alone and combined with DRO, on the self-injurious behavior in a woman with profound mental retardation and atypical psychosis

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Abstract

The effects of haloperidol, alone and combined with differential reinforcement of other behavior (DRO) on self-injurious behavior (SIB) of a woman with profound mental retardation and atypical psychosis were evaluated. Haloperidol, alone and combined with DRO, produced large reductions in SIB and injuries resulting from SIB. Response to environmental stimuli improved, meal refusal decreased significantly, her weight increased to an acceptable range, and sleep stabilized. SIB, meal refusal, sleep difficulties, weight loss, and inconsistent response to environmental stimuli appeared to be components of atypical psychosis that was responsive to low-dose haloperidol in combination with DRO. Treatment effects were maintained at a 27-month follow-up.

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Authors and Affiliations

  1. Center for the Retarded, Inc., Houston, Texas

    Deborah L. Grossett

  2. Richmond State School, 2100 Preston Street, 77469-1499, Richmond, Texas

    Don E. Williams

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  1. Deborah L. Grossett
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  2. Don E. Williams
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Grossett, D.L., Williams, D.E. Effects of haloperidol, alone and combined with DRO, on the self-injurious behavior in a woman with profound mental retardation and atypical psychosis. J Dev Phys Disabil 7, 147–154 (1995). https://doi.org/10.1007/BF02684959

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