Abstract
We studied the effects of long-term therapy with horseradish peroxidase administered orally to mice with experimental leprosy. Horseradish peroxidase stimulated phagocyte myeloperoxidase activity that correlated with their functional activity, reduced leukocytosis, and produced no adverse effects on the liver.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
N. I. Bakhov, L. Z. Aleksandrova, and V. N. Titov,Lab. Delo, No. 6, 3–12 (1988).
Laboratory Studies in Clinical Practice [in Russian], Ed. V. V. Men'shikov, Moscow (1987).
A. K. Maslov and A. A. Yushchenko,Arkh. Pat., No. 11, 51–54 (1988).
N. V. Beeching and C. J. Ellis,J. Antimicrob. Chemother.,10, 81–83 (1982).
R. C. Graham and M. J. Karnovsy,J. Histochem. Cytochem.,14, 291–302 (1966).
P. Jamet,Int. J. Lepr.,63, 195–201 (1995).
Laboratory Techniques for Leprosy, Geneva (1987).
C. C. Shepard,J. Exp. Med.,112, 445–454 (1960).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 7, pp. 83–87, July, 2000
Rights and permissions
About this article
Cite this article
Maslov, A.K., Luzhnova, S.A. Effects of peroxidase therapy on functional state of the liver and phagocytes and blood cell counts in mice with experimental leprosy. Bull Exp Biol Med 130, 682–686 (2000). https://doi.org/10.1007/BF02682105
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02682105