Abstract and Summary
High yields (85%) of 6-fatty acid esters ofl-ascorbic acid were obtained by reactingl-ascorbic acid (1.2 M) in 98~99% sulfuric acid for 36 hr at 20 C with 36% excess fatty acid. In concentrated sulfuric acid,l-ascorbic acid was rapidly sulfated to produce mainlyl-ascorbyl 6-sulfate, which slowly reacted with fatty acid to producel-ascorbyl 6-acylate.
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Cousins, R.C., Seib, P.A., Hoseney, R.C. et al. Synthesis of 6-fatty acid esters ofl-ascorbic acid. J Am Oil Chem Soc 54, 308–312 (1977). https://doi.org/10.1007/BF02672431
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DOI: https://doi.org/10.1007/BF02672431