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Serum hormone levels in British and rural Chinese females

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Abstract

The comparison of blood levels of oestradiol, testosterone, prolactin, and sex-hormone binding globulin (SHBG) was made of 3250 rural Chinese and 300 British women, aged 35 to 64. To reduce the number of assays performed the blood samples were combined so as to form 390 and 30 pools, respectively.

The Chinese had significantly less oestradiol and testosterone. Prolactin levels were similar in both races. SHBG was significantly lower in postmenopausal British women. In the Chinese women, testosterone was positively and prolactin negatively correlated with breast cancer mortality.

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Authors and Affiliations

  1. Cancer Epidemiology Unit, Radcliffe Infirmary, Imperial Cancer Research Fund, OX2 6HE, Oxford, UK

    D. Y. Wang

  2. Department of Clinical Endocrinology, Imperial Cancer Research Fund, Lincoln's Inn Fields, WC2A 3PX, London, UK

    T. J. A. Key

  3. Department of Preventive Medicine, Parkview Medical Building A201, University of Southern California School of Medicine, 1420 San Pablo Street, 90033-9987, Los Angeles, California, USA

    M. C. Pike

  4. Cancer Studies Unit, Nuffield Department of Clinical Medicine, University of Oxford, Radcliffe Infirmary, OX2 6HE, Oxford, UK

    J. Boreham

  5. Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medicine, Beijing, China

    J. Chen

Authors
  1. D. Y. Wang
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  2. T. J. A. Key
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  3. M. C. Pike
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  4. J. Boreham
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  5. J. Chen
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Wang, D.Y., Key, T.J.A., Pike, M.C. et al. Serum hormone levels in British and rural Chinese females. Breast Cancer Res Tr 18 (Suppl 1), S41–S45 (1991). https://doi.org/10.1007/BF02633526

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  • DOI: https://doi.org/10.1007/BF02633526

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