Skip to main content

Advertisement

SpringerLink
Log in

Primary multiple malignancy of the colon and rectum

Report of 230 cases

  • Published:
Diseases of the Colon & Rectum

Summary and Conclusions

A series of 2,508 patients with malignancy of the large intestine has been reviewed to determine the incidence of primary multiple neoplasms, which proved to be 9.1 per cent. Attention is directed to the frequency of involvement of the colon, rectum and other organs. It is recommended that prior to performing surgical operations on the colon, the various systems be thoroughly evaluated; that during the operation, meticulous exploration be performed and colonoscopy be utilized. After surgery, all patients should be checked clinically and radiologically at regular intervals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Albrecht, P.: Über die Multiplizität primärer maligner Geschwülste. Oncologia.5: 12, 1952.

    PubMed  CAS  Google Scholar 

  2. Bacon, H. E.: Multiple malignant tumors with involvement of the lower bowel: Report of multiple primary and contact growths. Am. J. Cancer.35: 243, 1939.

    Google Scholar 

  3. Bacon, H. E.: Anus, Rectum, Sigmoid Colon: Diagnosis and Treatment. Ed. 3, Philadelphia, J. B. Lippincott Company, 1949, vol. 2, p. 555.

    Google Scholar 

  4. Bacon, H. E.: Cancer of the Colon, Rectum and Anal Canal. Ed. 1, Philadelphia, J. B. Lippincott Company, 1964, p. 217.

    Google Scholar 

  5. Bacon, H. E. and O. C. Gass: Multiple primary malignant neoplasms of the rectum and sigmoid colon: Report of five additional cases. Am. J. Surg.68: 240, 1945.

    Article  Google Scholar 

  6. Bacon, H. E. and R. A. McGregor: Multiple primary malignant tumors of the colon: Report of 141 cases. J. Internat. Coll. Surgeons.28: 618, 1957.

    PubMed  CAS  Google Scholar 

  7. Bacon, H. E. and M. C. Tavenner: Multiple primary malignant tumors involving the colon and rectum: Report of ninety-four cases. Am. J. Surg.83: 55, 1952.

    Article  PubMed  CAS  Google Scholar 

  8. Behrend, M.: Carcinoma of colon: Treatment depending on location of lesions. Surg., Gynec. & Obst.65: 505, 1937.

    Google Scholar 

  9. Berson, H. L. and L. Berger: Multiple carcinomas of the large intestine. Surg., Gynec. & Obst.80: 75, 1945.

    Google Scholar 

  10. Billroth, I.: Die Allgemeine Chirurgische Pathologie und Therapie. Berlin, G. Reimer, 1889, p. 908.

    Google Scholar 

  11. Bonser, G. M. and L. M. Waiman: Further experimental study of antagonism between one malignant tumour and appearance of another in same animal. J. Path. & Bact.52: 263, 1941.

    Article  Google Scholar 

  12. Boyd, W.: Textbook of Pathology. Ed. 3, Philadelphia, Lea & Febiger, 1938, pp. 296; 558.

    Google Scholar 

  13. Brindley, G. V. and J. S. Rice, Jr.: Multiple primary malignancies of the large intestine. S. Clin. North America.32: 1499, 1952.

    Google Scholar 

  14. Bunting, C. H.: Multiple primary carcinoma of the ileum. Bull. Johns Hopkins Hosp.15: 389, 1904.

    Google Scholar 

  15. Cramer, W.: On an antagonism in the development of malignancy in two different organs. J. Path. & Bact.43: 77, 1936.

    Article  Google Scholar 

  16. Czerny: Aus der Heidelberger chirurgischen Klinik: Nachtrag zur Darmresection. Berl. klin. Wchnschr.17: 683, 1880.

    Google Scholar 

  17. Desaive, P. and E. Monnoyer: Considérations cliniques et pathologiques au sujet des cancers recto-coliques multiples. Acta gastroenterol. belg.13: 999, 1950.

    PubMed  CAS  Google Scholar 

  18. Dukes, C.: The hereditary factor in polyposis intestini, or multiple adenomata. Cancer Rev.5: 241, 1930.

    Google Scholar 

  19. Ehrlich, P.: Experimentelle Studien an Mäusetumoren. Ztschr. Krebsforsch.5: 50, 1907.

    Google Scholar 

  20. Fenger, C.: Double carcinoma of the colon. J.A.M.A.11: 606, 1888.

    Google Scholar 

  21. Gaylord, H. R., G. H. A. Clowes and F. W. Baeslack: An anti-carcinoma serum. Med. News.86: 91, 1905.

    Google Scholar 

  22. Ginzburg, L. and D. A. Dreiling: Successive independent (metachronous) carcinoma of the colon. Ann. Surg.143: 117, 1956.

    Article  PubMed  CAS  Google Scholar 

  23. Goligher, J. C., C. E. Dukes and H. J. R. Bussey: Local recurrences after sphinctersaving excisions for carcinoma of the rectum and rectosigmoid. Brit. J. Surg.39: 199, 1951.

    Article  PubMed  CAS  Google Scholar 

  24. Greene, H. N. and J. S. Strauss: Multiple primary tumors in the rabbit. Cancer.2: 673, 1949.

    Article  PubMed  CAS  Google Scholar 

  25. Hiel, M.: Cancers primitifs multiples rectocoliques et association d’une tumeur gastrique à une tumeur rectocolique. Acta chir. belg.52: 777, 1953.

    PubMed  CAS  Google Scholar 

  26. Hurt, H. H. and A. C. Broders: Multiple primary malignant neoplasms. J. Lab. & Clin. Med.18: 765, 1933.

    Google Scholar 

  27. Kirshbaum, J. D. and F. L. Shiveley, Jr.: Multiple primary malignant tumors. J. Lab. & Clin. Med.24: 283, 1938.

    Google Scholar 

  28. Lockhart-Mummery, J. P. and C. E. Dukes: Familial adenomatosis of the colon and rectum: Its relationship to cancer. Lancet.2: 586, 1939.

    Article  Google Scholar 

  29. Lombard, H. L. and S. Warren: Association of other malignant tumors with cancer of the skin. Am. J. Pub. Health.33: 533, 1943.

    PubMed  CAS  Google Scholar 

  30. McGregor, R. A. and H. E. Bacon: Multiple cancers in colon surgery: Report of 162 cases. Surgery.44: 828, 1958.

    PubMed  CAS  Google Scholar 

  31. Mercanton, F.: Des carcinomes primaires multiples. Rev. méd. Suisse Rom.13: 173, 1893.

    Google Scholar 

  32. Michaelis, L.: Weitere experimentelle Untersuchungen über Tierkrebs. Deutsche med. Wchnschr.33: 826, 1907.

    Google Scholar 

  33. Mider, G. B., J. A. Schilling, J. C. Donovan and E. S. Rendall: Multiple cancer: A study of other cancers arising in patients with primary malignant neoplasms of the stomach, uterus, breast, large intestine, or hematopoietic system. Cancer.5: 1104, 1952.

    Article  PubMed  CAS  Google Scholar 

  34. Moertel, C. G., J. A. Bargen and M. B. Dockerty: Multiple carcinomas of the large in testine and a study of 261 cases. Gastroenterology.34: 85, 1958.

    PubMed  CAS  Google Scholar 

  35. Muller, R. B.: Uber multiple, nichtsytematisierte Primarcarcinome und ihre Haufigkeit. Ztschr. Krebsforsch.31: 339, 1930.

    Article  Google Scholar 

  36. Owen, L. J.: Multiple malignant neoplasms. J.A.M.A.76: 1329, 1921.

    Google Scholar 

  37. Peller, S.: Carcinogenesis as a means of reducing cancer mortality. Lancet.2: 552, 1936.

    Article  Google Scholar 

  38. Rankin, F. W. and C. C. Johnston: Multiple malignant lesions of the large bowel. Internat. Clin.2(n.s.4): 246, 1941.

    Google Scholar 

  39. Schmidt, E. A.: Incidence of multiple primary tumors and the problem of acquired cancer immunity. Radiology.39: 208, 1942.

    Google Scholar 

  40. Slaughter, D. P.: The multiplicity of origin of malignant tumors: Collective review. Internat. Abstr. Surg.79: 89, 1944.

    Google Scholar 

  41. Spear, H. C. and S. C. Brainard: Cancer of the large bowel-an analysis of 580 lesions. Ann. Surg.134: 934, 1951.

    Article  PubMed  CAS  Google Scholar 

  42. Stalker, D. K., R. B. Phillips and J. deJ. Pemberton: Multiple primary malignant lesions. Surg., Gynec. & Obst.68: 595, 1939.

    Google Scholar 

  43. Stenstrom, J. D. and H. S. Ford: Carcinoma of the colon: Analysis of 1,000 cases with particular reference to polyps and multiple carcinoma. Am. J. Surg.88: 1, 1954.

    Article  Google Scholar 

  44. Thomas, J. F., M. B. Dockerty and J. M. Waugh: Multiple primary carcinomas of the large intestine. Cancer.1: 564, 1948.

    Article  Google Scholar 

  45. Thorlakson, P. H. T.: The incidence of multiple malignant growths of the large bowel. Manitoba M. Rev.32: 158, 1952.

    PubMed  CAS  Google Scholar 

  46. Tondreau, R. L.: Multiple primary carcinomas of the large intestine. Am. J. Roentgenol.71: 794, 1954.

    CAS  Google Scholar 

  47. Ward, R.: Radium treatment of epitheliomata of the skin. Brit. M. J.2: 511, 1930.

    Google Scholar 

  48. Warren, S. and T. Ehrenreich: Multiple primary malignant tumors and susceptibility to cancer. Cancer Res.4: 554, 1944.

    Google Scholar 

  49. Warren, S. and O. Gates: Multiple primary malignant tumors: Survey of literature and statistical study. Am. J. Cancer.16: 1358, 1932.

    Google Scholar 

  50. Watson, T. A.: Incidence of multiple cancer. Cancer.6: 365, 1953.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Temple University Medical Center, USA

    Moises Diamante M.D. (Resident in Proctologic Surgery) & Harry E. Bacon M.D.

  2. Philadelphia, Pennsylvania

    Moises Diamante M.D. (Resident in Proctologic Surgery)

Authors
  1. Moises Diamante M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Harry E. Bacon M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Read at the meeting of the American Proctologic Society, Cleveland, Ohio, June 20 to 22, 1966.

Supported in part by grant, Research Foundation American Proctologic Society.

About this article

Cite this article

Diamante, M., Bacon, H.E. Primary multiple malignancy of the colon and rectum. Dis Colon Rectum 9, 441–446 (1966). https://doi.org/10.1007/BF02617441

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02617441

Keywords

Search

Navigation