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Hormonal and metabolic changes in oncology patients subjected to general hyperthermia and ways for their correction

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Journal of Engineering Physics and Thermophysics Aims and scope

Abstract

Hormonal-metabolic changes in oncology patients subjected to general hyperthermia (GHT) result in enhancement of free-radical oxidation and accumulation of endotoxins under the conditions of violation of their targeted transport to detoxication. A pathogenesis-matched stress-limiting program is developed that allows optimization of the GHT treatment.

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Abbreviations

ACTH:

adrenocorticotropic hormone

AIAT:

alanine aminotransferase

AsAT:

aspartate aminotransferase

AOS:

antioxidation system

DB:

double bonds of the lipid fraction of serum

IRI:

immunoreactive insulin

AH:

artificial hyperglycemia

CPhK:

creatine phosphokinase

MDA:

malonic dialdehyde

MWM:

mean-weight molecules

LA:

lactic acid

GHT:

general hyperthermia

LP:

lipid peroxidation

PAA:

pyroacemic acid

FRO:

free-radical oxidation

FFA:

free fatty acids

STH:

somatropic hormone

SOD:

superoxide dismutase

cAMPh:

cyclic adenosin-3′, 5′-monophosphate

cGMPh:

cyclic guanosine-3′, 5′, monophosphate

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Authors
  1. V. I. Prohkorova
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  2. A. A. Mashevskii
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  3. S. V. Lappo
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  4. T. P. Tsyrus’
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  5. M. S. Abramovich
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Additional information

Scientific Research Institute of Oncology and Medical Radiology of the Ministry of Public Health of Belarus, Minsk, Belarus. Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 69, No. 3, pp. 443–450, May–June, 1996.

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Prohkorova, V.I., Mashevskii, A.A., Lappo, S.V. et al. Hormonal and metabolic changes in oncology patients subjected to general hyperthermia and ways for their correction. J Eng Phys Thermophys 69, 354–359 (1996). https://doi.org/10.1007/BF02606958

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  • DOI: https://doi.org/10.1007/BF02606958

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