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Sodium transport inhibitors in pregnancy-induced hypertension

Cardiovascular Drugs and Therapy volume 4, pages 351–356 (1990)Cite this article

Summary

In blacks and whites of similar socioeconomic background, the incidence of pregnancy-induced hypertension (PIH) is probably the same. In underdeveloped coutries, however, PIH is often a life-threatening complication of pregnancy. Recent theories as to the etiology of PIH include the suggestion that vascular tone may be increased as a result of inhibition of active sodium transport in vascular smooth muscle. This may be the result of an inhibitor of sodium transport present in the serum. The literature concerning the demonstration of endogenous sodium transport inhibitors and endogenous digoxinlike immunoreactivity (EDLI) in PIH is reviewed and discussed.

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  1. Renal Laboratory, St. Thomas' Hospital and Medical School, SE1 7EH, London, UK

    Lucilla Poston PhD

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  1. Lucilla Poston PhD
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Poston, L. Sodium transport inhibitors in pregnancy-induced hypertension. Cardiovasc Drug Ther 4, 351–356 (1990). https://doi.org/10.1007/BF02603175

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  • DOI: https://doi.org/10.1007/BF02603175

Key words

  • Sodium transport
  • pregnancy-induced hypertension
  • endogenous digoxinlike immunoreactivity
  • sodium transport inhibitor