Zusammenfassung
Grundlagen
Bronchoplastische Resektionen des nichtkleinzelligen Bronchialkarzinoms (NSCLC) beinhalten das Risiko der Anastomoseninsuffizienz und können mit einer hohen Rate an Lokalrezidiven behaftet sein. Unsere Erfahrungen mit dieser Technik werden vorgestellt.
Methodik
In einem 12-Jahres-Zeitraum wurden unter 1478 Operationen wegen NSCLC 102 bronchoplastische Resektionen (6,9%) durchgeführt. Bei 74 Lobektomien, 19 Bilobektomien und 9 Pneumonektomien erfolgten 72 Manschettenresektionen, 28 Bronchuskeil- und 2 Bifurkationsresektionen. 95 Männer und 7 Frauen hatten ein mittleres Alter von 60±6 Jahren.
Ergebnisse
Eine reversible Atelektase trat in 6% auf, in 4% wurde eine Anastomosendehiszenz beobachtet. In 81% erfolgte eine R0-Resektion. Die 30-Tage-Letalität betrug 4%. Die 5-Jahres-Überlebensraten der kurativ operierten Patienten betrugen für die Stadien I, II und III 77%, 55% und 26%.
Schlußfolgerungen
Bronchoplastische Resektionen stellen eine sichere Therapieoption bei der Behandlung des zentralen NSCLC dar.
Summary
Background
Bronchoplastic resections for non-small cell lung cancer (NSCLC) are reported to carry the risk of anastomotic complications and to have a high rate of local recurrence. Our experience with this technique is reported.
Methods
During the past 12 years, among 1478 operations for Non-Small-Cell Lung Cancer (NSCLC), 102 (6,9%) bronchoplastic resections were performed. There were 74 lobectomies, 19 bilobectomies and 9 pneumonectomies done by means of 72 sleeve-, 28 wedge resections and 2 resections of the tracheal bifurcation in 95 men and 7 women with a mean age of 60±6 years.
Results
Reversible atelectasis was observed in 6%, whereas anastomotic dehiscence occurred in 4%. Local complete resection was achieved in 81%. The 30-day-mortality amount to 4%. 5-year survival rate was 77%, 55% and 26% for stages I, II and III.
Conclusions
Bronchoplastic resections represent a safe therapeutic option in the operative management of centrally located NSCLC.
Literatur
Allison P: Course of Thoracic Surgery in Groningen. 1954.
Barthlen W, Prauer HW, Holzel D, Schubert-Fritschle G: Actuarial survival and prognostic factors of bronchial cancer. Langenbecks Arch Chir 1993;378:26–31.
Benneth F, Smith A. A Twenty-year Analysis of the Results of Sleeve Resection for Primary Bronchogenic Carcinoma. J Thorac Cardiovasc Surg 1978;76:840.
D'Abreu A.L., MacHale S.J.: Bronchial “Adenoma” Treated by Local Resection and Reconstruction of the Left Main Bronchus. Br J Surg 1952;39:355.
Deslauriers J, Mehran RJ, Guimont C Brisson J: Staging and management of lung cancer: sleeve resection. World J Surg 1993;17:712–718.
Frist WH, Mathisen DJ, Hilgenberg AD, Grillo HC: Bronchial sleeve resection with and without pulmonary resection. J Thorac Cardiovasc Surg 1987;93:350–357.
Gebauer P: Bronchial Resection and Anastomosis. J Thorac Surg 1953;26:241.
Kaplan EL, Meier P: Non-parametric estimation from incomplete observations. J Am Statistical Assoc 1958;53:457.
Liewald F, Hatz RA, Dienemann H, Sunder-Plassmann L: Importance of microscopic residual disease at the bronchial margin after resection for non-small-cell carcinoma of the lung. J Thorac Cardiovasc Surg 1992;104:408–412.
Lowe JE, Bridgman AH, Sabiston D Jr: The role of bronchoplastic procedures in the surgical management of benign and malignant pulmonary lesions. J Thorac Cardiovasc Surg 1982;83:227–234.
Maggi G, Casadio C, Pischedda F, Cianci R, Ruffini E, Filosso P: Bronchoplastic and angioplastic techniques in the treatment of bronchogenic carcinoma. Ann Thorac Surg 1993;55:1501–1507.
Paulson D, Urschel J, McNamara J, Shaw R: Bronchoplastic Procedures for Bronchogenic Carcinoma. J Thorac Cardiovasc Surg 1955;59:38.
Price T: Conserving Resection of the Bronchial Tree. J.R. College of Surgery 1956;1–2:169.
Tedder M, Anstadt MP, Tedder SD, Lowe JE: Current morbidity, mortality, and survival after bronchoplastic procedures for malignancy. Ann Thorac Surg 1992;54:387–391.
UICC: TNM classification of malignant tumours. 4th. ed. Berlin-Heidelberg-New York-Tokyo, Springer, 1987.
Vogt-Moykopf I, Fritz T, Bulzebruck H, Merkle N, Daskos G, Meyer G: Bronchoplastic and angioplastic operations in bronchial carcinoma. Langenbecks Arch Chir 1987;371:85–101.
Vogt-Moykopf I, Toomes H, Heinrich S: Sleeve resection of the bronchus and pulmonary artery for pulmonary lesions. Thorac Cardiovasc Surg 1983;31:193–198.
Watanabe Y, Kobayashi H, Murakami S, Sawa S, Shinagawa M, Iwa, T: Bilateral sleeve lobectomy for metachronous multiple primary lung cancer. Jpn J Surg 1986;16:56–61.
Watanabe Y, Shimizu J, Oda M, Hayashi Y, Watanabe S, Yazaki U, Iwa T: Results in 104 patients undergoing bronchoplastic procedures for bronchial lesions. Ann Thorac Surg 1990;50: 607–614.
Weisel R, Cooper J, Delarue N, Theman T, Todd T, Pearson G: Sleeve Lobectomy for Carcinoma of the Lung. J Thorac Cardiovasc Surg 1979;78:839 ff.
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Müller, C., Schinkel, C., Hoffmann, H. et al. Technik und Ergebnisse bronchoplastischer Resektionen bei nichtkleinzelligem Bronchialkarzinom. Acta Chir Austriaca 28, 74–78 (1996). https://doi.org/10.1007/BF02602605
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DOI: https://doi.org/10.1007/BF02602605