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Newer concepts of cancer of the colon and rectum: Delayed hypersensitivity responses of patients with carcinoma of the colon and other solid tumors

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Diseases of the Colon & Rectum

Summary

Eighty-nine patients were skin-tested with four delayed allergens: old tuberculin, mumps, streptokinase-streptodornase, andTrichophyton. Forty-eight of these patients, including 43 with carcinoma of the colon, had nonreticuloendothelial tumors. Patients with tumors were otherwise in good health. There were significant differences between the delayed skin sensitivity of patients with cancer and those without cancer, and between the responses to challenge with streptokinase-streptodornase of patients with metastases and those without metastases. The presence of cancer decreased responsiveness, and metastases limited responsiveness still further.

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Authors and Affiliations

  1. College of Physicians and Surgeons of Columbia, University Presbyterian Hospital, 622 W. 168th St., 10032, New York, New York

    Barry S. Kronman M.D.

  2. Department of Surgery, University of Arizona, 85719, Tucson, Arizona

    Howard M. Shapiro M.D.

  3. Department of Surgery, New York University Medical Center, 10016, New York, New York

    S. Arthur Locallo M.D.

Authors
  1. Barry S. Kronman M.D.
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  2. Howard M. Shapiro M.D.
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  3. S. Arthur Locallo M.D.
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Kronman, B.S., Shapiro, H.M. & Locallo, S.A. Newer concepts of cancer of the colon and rectum: Delayed hypersensitivity responses of patients with carcinoma of the colon and other solid tumors. Dis Colon Rectum 15, 106–110 (1972). https://doi.org/10.1007/BF02587255

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  • DOI: https://doi.org/10.1007/BF02587255

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