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Argyrophil mucus-secreting adenocarcinoma of the colon and sebocystomatosis: Report of a case

  • Published:
Diseases of the Colon & Rectum

Summary

An infiltrating but localized mucus-secreting adenocarcinoma was found in the ascending colon of a 76-year-old woman who also had cutaneous sebocystomatosis. The Sevier-Munger technique revealed argyrophil granules in most of the neoplastic cells. Only once before have PAS-positive and argentaffin granules (argyrophil in this case) been demonstrated in the cytoplasm of the same malignant cells. Although cancer of the colon and cutaneous epidermal cysts constitute a clear-cut syndrome (Gardner's syndrome), malignancy of the colon is an exceptional complication of sebocystomatosis. Differentiation of the cutaneous condition should be made by skin biopsies.

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Authors and Affiliations

  1. Cátedra de Patologia Ia, Facultad de Medicina de La Plata, República Argentina

    Ricardo Drut M.D.

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  1. Ricardo Drut M.D.
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Drut, R. Argyrophil mucus-secreting adenocarcinoma of the colon and sebocystomatosis: Report of a case. Dis Colon Rectum 17, 700–704 (1974). https://doi.org/10.1007/BF02587125

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  • DOI: https://doi.org/10.1007/BF02587125

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