Abstract
Cronkhite–Canada Syndrome (CCS) is a non-hereditary disorder characterized by multiple non-neoplastic polyps in the gastrointestinal tract. CCS is considered to be a rare disease worldwide, but the majority of reported cases are from Japan. Polyps are frequently detected particularly in the stomach and colon, and in more than half of cases, polyps are also detected in the small intestine. Cutaneous manifestations such as alopecia, onychodystrophy, and hyperpigmentation, as well as dysgeusia, are also characteristic. Corticosteroids are highly effective in the treatment of this disease. However, relapses occur in some cases and the incidence of gastrointestinal malignancies is higher than in the general population. Therefore, early induction and maintenance of remission as well as regular observation over a long period are necessary.
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Hokari, R., Hisamatsu, T., Higashiyama, M. (2022). Cronkhite–Canada Syndrome. In: Hokari, R., Hisamatsu, T. (eds) Atlas of Cronkhite-Canada Syndrome. Springer, Singapore. https://doi.org/10.1007/978-981-19-0652-7_1
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DOI: https://doi.org/10.1007/978-981-19-0652-7_1
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