Abstract
1,1,1-Tris(2-hydroxyethyl)amine-2-acylimide (I) was prepared by the reaction of hydrazine hydrate, ethylene oxide, and fatty acid methyl ester. Reaction conditions such as solvent, reaction temperature, and molar ratio of reactants were investigated, and (I) was obtained in 73% yield by heating an isopropanol solution of hydrazine hydrate, methyl palmitate, and ethylene oxide in molar ratio of 1:6:6 at 80 C for 2 hr.
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Ikeda, I., Katsura, T.F. & Okahara, M. Synthesis of 1,1,1-Tris(2-hydroxyethyl)amine-2-acylimide. J Am Oil Chem Soc 53, 537–540 (1976). https://doi.org/10.1007/BF02586255
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DOI: https://doi.org/10.1007/BF02586255