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Increase ofS-(1,2-dicarboxyethyl)glutathione in regenerating rat liver

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Research in Experimental Medicine

Summary

Changes in the level ofS-(1,2-dicarboxyethyl)glutathione (DCE-GS) with time were determined during regeneration of rat liver after partial hepatectomy. The DCE-GS level increased in regenerating rat liver, reaching a maximum level (4.7-fold) on day 2 and reverted to the normal level in 1 week. During the liver regeneration process, the activity of DCE-GS-synthesizing enzyme in the liver retained its control level, while the level of glutathione—a substrate of the enzyme in the liver—fluctuated in parallel with that of DCE-GS.

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Tsuboi, S., Miyazaki, M., Kondo, Y. et al. Increase ofS-(1,2-dicarboxyethyl)glutathione in regenerating rat liver. Res. Exp. Med. 192, 281–286 (1992). https://doi.org/10.1007/BF02576284

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  • DOI: https://doi.org/10.1007/BF02576284

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