Abstract
Thirty mongrel dogs underwent 4000- or 5000-rad single treatment orthovoltage irradiation to the pelvis according to the nominal standard dose equation. Following a resting period of six months, 21 dogs were randomized to low anterior resection with either stapled or hand-sewn anastomoses. Anastomotic leaks were evaluated on clinical and radiographic grounds. The radiographic leak rate was 81 percent for sutured and 0 percent for stapled anastomoses. The clinical leak rate was 18 percent for sutured and 0 percent for stapled anastomoses. The difference between the 4000- and 5000-rad groups was not significant. The data suggest that late effects of irradiation do not preclude the safe construction of low anterior anastomoses, and that the circular stapling device is superior to hand-sewn techniques.
Similar content being viewed by others
References
Morgenstern L, Thompson R, Friedman NB. The modern enigma of radiation enteropathy: sequelae and solutions. Am J Surg 1977;134:166–2.
Bubrick MP, Rolfsmeyer ES, Schauer RM, et al. Effects of high-dose and low-dose preoperative irradiation on low anterior anastomoses in dogs. Dis Colon Rectum 1982;25:406–15.
Schauer RM, Bubrick MP, Feeney DA, et al. Effects of low-dose preoperative irradiation on low anterior anastomosis in dogs. Dis Colon Rectum 1982;25:401–5.
Blake DP, Bubrick MP, Kochsiek GG, et al. Low anterior anastomotic dehiscence following preoperative irradiation with 6000 rads. Dis Colon Rectum 1984;27:176–81.
Morgenstern L, Sanders G, Wahlstrom E, Yadegar J, Amodeo P. Effect of preoperative irradiation on healing of low colorectal anastomoses. Am J Surg 1984;147:246–9.
Localio SA, Pachter HL, Gouge TH. The radiation-injured bowel. Surgery Ann 1979;11:181–205.
Galland RB, Spencer J. Surgical aspects of radiation injury to the intestine. Br J Surg 1979;66:135–8.
Deveney CW, Lewis FR Jr, Schrock TR. Surgical management of radiation injury of the small and large intestine. Dis Colon Rectum 1976;19:25–9.
Dencker H, Johnsson JE, Liedberg G, Tibblin S. Surgical aspects of radiation injury to the small and large intestines. Acta Chir Scand 1971;137:692–5.
O'Connor TW, Rombeau JL, Levine HS, Turnbull RB Jr. Late development of colorectal cancer subsequent to pelvic irradiation. Dis Colon Rectum 1979;22:123–8.
Palmer JA, Bush RS. Radiation injuries to the bowel associated with the treatment of carcinoma of the cervix. Surgery 1976; 80:458–64.
Marks G. Combined abdominotranssacral reconstruction of the radiation-injured rectum. Am J Surg 1976;131:54–9.
Author information
Authors and Affiliations
About this article
Cite this article
Meese, D.L., Bubrick, M.P., Paulson, G.L. et al. Safety of low anterior resection in the presence of chronic radiation changes in dogs. Dis Colon Rectum 29, 22–26 (1986). https://doi.org/10.1007/BF02555279
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02555279