Abstract
Case reports of three teenage patients with nonfamilial diffuse juvenile polyposis are presented to illustrate the considerable morbidity and significant growth retardation that may occur. Although generally considered to have no malignant potential, histologic findings revealed features ranging from adenomatous change to severe dysplasia. It is suggested that a conservative approach may not always be appropriate in this condition.
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References
Louw JH. Polypoid lesions of the large bowel in children. S Afr Med J 1972;46:1347–52.
Veale AM, McColl I, Bussey HJ, Morson BC. Juvenile polyposis coli. J Med Genet 1966;3:5–16.
Sachatello CR, Pickren JW, Grace JT Jr. Generalized juvenile gastrointestinal polyposis: a hereditary syndrome. Gastroenterology 1970;58:699–708.
Roth SI, Helwig EB. Juvenile polyps of the colon and rectum. Cancer 1963;16:468–79.
Smilow PC, Pryor CA Jr, Swinton NW. Juvenile polyposis coli: a report of three patients in three generations of one family. Dis Colon Rectum 1966;9:248–54.
Lynch HT, Krush AJ. Heredity and adenocarcinoma of the colon. Gastroenterology 1967;53:517–27.
Stemper TJ, Kent TH, Summers RW. Juvenile polyposis and gastrointestinal carcinoma: a study of a kindred. Ann Intern Med 1975;83:639–46.
Kaschula RO. Mixed juvenile, adenomatous and intermediate polyposis coli: report of a case. Dis Colon Rectum 1971;14:368–74.
Beacham CH, Shields HM, Raffensperger EC, Enterline HT. Juvenile and adenomatous gastrointestinal polyposis. Dig Dis Sci 1978;23:1137–43.
Bussey HJ, Veale AM, Morson BC. Genetics of gastrointestinal polyposis. Gastroenterology 1978;74:1325–30.
Goodman ZD, Yardley JH, Milligan FD. Pathogenesis of colonic polyps in multiple juvenile polyposis: report of a case associated with gastric polyps and carcinoma of the rectum. Cancer 1979;43:1906–13.
Monga G, Mazzucco G, Rossini FP, Presti F. Colorectal polyposis with mixed juvenile adenomatous patterns. Virchows Arch [A] 1979;382:355–60.
Sandler RS, Lipper S. Multiple adenomas in juvenile polyposis. Am J Gastroenterol 1981;75:361–6.
Grigioni WF, Alampi G, Martinelli G, Piccaluga A. Atypical juvenile polyposis. Histopathology 1981;5:361–76.
Järvinen H, Franssila KO. Familial juvenile polyposis coli: increased risk of colorectal cancer. Gut 1984;25:792–800.
Ramaswamy G, Elhosseiny AA, Tchertkoff V. Juvenile polyposis of the colon with atypical adenomatous changes and carcinomain situ: report of a case and review of the literature. Dis Colon Rectum 1984;27:393–8.
Farthing MJ, McLean AM, Bartram CI, Baker LR, Kumar PJ. Radiologic features of the jejunum in hypoalbuminemia. AJR 1981;136:883–6.
McColl I, Bussey HJ, Veale AM, Morson BC. Juvenile polyposis coli. Proc R Soc Med 1974;57:896–7.
Kozuka S. Nature of juvenile polyps in the large intestine. Acta Pathol Jpn 1976;26:509–18.
Reid JD. Intestinal carcinoma in the Peutz-Jeghers syndrome. JAMA 1974;229:883–4.
Perzin KH, Bridge MF. Adenomatous and carcinomatous changes in hamartomatous polyps of the small intestine (Peutz-Jeghers syndrome): report of a case and review of the literature. Cancer 1982;49:971–83.
Grotsky HW, Rickert RR, Smith WD, Newsome JF. Familial juvenile polyposis coli: a clinical and pathologic study of a large kindred. Gastroenterology 1982;82:494–501.
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Support from the Medical Research Council of South Africa is gratefully acknowledged.
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Gilinsky, N.H., Elliot, M.S., Price, S.K. et al. The nutritional consequences and neoplastic potential of juvenile polyposis coli. Dis Colon Rectum 29, 417–420 (1986). https://doi.org/10.1007/BF02555065
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DOI: https://doi.org/10.1007/BF02555065