Abstract
The autopsy findings of 100 patients who had a resection for largebowel cancer and who were classified by a clinicopathologic staging system were analyzed. Seventy patients had carcinoma at autopsy. The value of this method of staging was assessed by relating the stage at operation to these findings. Forty-five per cent of early stage tumors (A or B) were found to have metastases. If the detection rate of occult metastases could be improved for stage A and B tumors, this might increase the prognostic accuracy of this staging system.
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References
Pheils MT, Barnett JE, Newland RC, MacPherson JG. Colorectal carcinoma: a prospective clinicopathological study. Med J Aust 1967;1(suppl):17–21.
Newland RC, Chapuis PH, Pheils MT, MacPherson JG. The relationship of survival to staging and grading of colorectal carcinoma: a prospective study of 503 cases. Cancer 1981; 47:1424–9.
Dukes CE. The classification of cancer of the rectum. J Pathol Bact 1932;35:323–32.
Nie NH, Hull CH, Jenkins JG, Steinbrenner, K, Bent DH. Statistical package for the social sciences. New York: McGraw-Hill, 1975.
Berkson J, Gage R. Calculation of survival rates for cancer. Proc Mayo Clin 1950;25:270–86.
Stearns MW. Staging colonic and rectal cancer. Int Adv Surg Oncol 1981;4:189–208.
Dukes DE, Bussey HJ. The spread of rectal cancer and its effect on prognosis. Br J Cancer 1958;12:309–20.
Nicholls RJ, Ritchie JK, Wadsworth J, Parks AG. Total excision of restorative surgery for carcinoma of the middle third of the rectum. Br J Surg 1979;66:625–7.
Finlay IG, Meek DR, Gray HW, Duncan JG, McArdle CS. Incidence and detection of occult hepatic metastases in colorectal carcinoma. Br Med J 1982;284:803–5.
Mooney B, Critchley M, Grime S, Taylor I. Portal vein liver scanning for early detection of liver metastases in colorectal cancer. Gut 1981;25:A436.
Editorial. Metastases in the liver. Br Med J 1981;282:2078–9.
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This study was supported in part by a grant from the Royal Australasian College of Surgeons.
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Chapuis, P.H., Dent, O.F., Newland, R.C. et al. A postmortem appraisal of a clinicopathologic staging system in large-bowel cancer. Dis Colon Rectum 26, 709–711 (1983). https://doi.org/10.1007/BF02554978
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DOI: https://doi.org/10.1007/BF02554978